...Abdulla A.-B. Badawy; Aryan M.A. Namboodiri; John R. Moffett We hypothesize that: (1) L -tryptophan (Trp) is greatly utilized and not depleted in pregnancy; (2) fetal tolerance is achieved in part through immunosuppressive kynurenine (Kyn) metabolites produced by the flux of plasma free (non...

...Veronica I. Landoni; Daiana Martire-Greco; Nahuel Rodriguez-Rodrigues; Paula Chiarella; Pablo Schierloh; Martin A. Isturiz; Gabriela C. Fernández Secondary infections due to post-sepsis immunosuppression are a major cause of death in patients with sepsis. Repetitive inoculation of increasing doses...

... of the underlying immunosuppression is only incompletely understood. In the present study, we investigated whether injury interferes with the function of the adaptive immune system in particular with the differentiation of antigen-specific T helper (Th)-cell responses in vivo . We used a mouse model for traumatic...

...Daiana Martire-Greco; Veronica I. Landoni; Paula Chiarella; Nahuel Rodriguez-Rodrigues; Pablo Schierloh; Barbara Rearte; Martin A. Isturiz; Gabriela C. Fernandez Secondary infections due to post-sepsis immunosuppression are a major cause of death in patients with sepsis. Strategies aimed...

... clones maintained their original functionality for culture periods of up to 100 days. adaptive regulatory T-cell (T reg -cell) cytokine release hepatitis C virus (HCV) immunosuppression T-cell cloning HCV (hepatitis C virus) efficiently establishes chronic persistency in the majority...

... risks as well as immunosuppressive-related risks. Procedure-related risks include bleeding, thrombosis, biliary puncture, discomfort, transient rise in serum transaminase and arteriovenous fistulae. Immunosuppressive-related risks include oral ulcers, anaemia, diarrhoea, weight loss, fatigue, LDL (low...

...David GOLDSMITH; Elizabeth A. CARREY; Stephen EDBURY; Ryszard T. SMOLENSKI; Piotr. JAGODZINSKI; H. Anne SIMMONDS The immunosuppressant MMF (mycophenolate mofetil) has increasingly replaced AZA (azathioprine) in renal transplantation. MMF is a prodrug of MPA (mycophenolic acid), which inhibits...

..., Finland (e-mail [email protected] ). 5 2 2003 19 5 2003 2 6 2003 2 6 2003 © 2003 The Biochemical Society 2003 acute pancreatitis flow cytometry human leucocyte antigen-DR (HLA-DR) immunosuppression multiple organ failure sensitivity and specificity...

... immediately before morning dosage of immunosuppressants. Mean of urinary protein excretion (meanProt) and mean of serum creatinine (meanCrea) were calculated from all available measurements in the most recent year. uET-1 and uBigET-1 were adjusted for urinary protein excretion by calculating uET-1/meanProt...

... characterized by tissue accumulation of propionic acid and methylmalonic acid respectively, it is possible that these compounds may act as immunosuppressants. We therefore investigated the effect of propionate and methylmalonate on cellular growth of human peripheral lymphocytes stimulated in vitro...