1-8 of 8
Keywords: inflammasome
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Clin Sci (Lond) (2023) 137 (5): 333–351.
Published: 01 March 2023
... will focus on the role of NACHT, leucin-rich repeat and pyrin-containing protein 3 (NLRP3) inflammasome in the pathophysiology of sepsis. NLRP3 inflammasome is a multiproteic intracellular complex activated by infectious pathogens through a two-step process resulting in the release of the pro-inflammatory...
Articles
Articles
Clin Sci (Lond) (2020) 134 (17): 2243–2262.
Published: 03 September 2020
.... The SASP is characterised by the release of inflammatory cytokines, elevated activation of the NLRP3 inflammasome, altered regulation of acetylcholine (ACh) nicotinic receptors, and abnormal NAD + metabolism. Therefore, SASP may be ‘druggable’ by small molecule therapeutics targeting those emerging...
Articles
Clin Sci (Lond) (2018) 132 (20): 2221–2239.
Published: 29 October 2018
...Cheng-Yi Chen; Chia-Yu Chen; Chang-Ching Liu; Chie-Pein Chen Preterm labor is associated with inflammation and infection. The mechanisms underlying the role of omega-3 fatty acid in inflammasome activation and prevention of preterm labor remain unknown. We hypothesized that omega-3 fatty acid can...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (17): 1901–1924.
Published: 05 September 2018
... Commons Attribution License 4.0 (CC BY-NC-ND) . Autoinflammatory Interferonopathy inflammasome interferon Periodic Fever Syndrome The phrase ‘ autoinflammatory disease ’ was proposed as an alternative to ‘ autoimmune disease ’ by McDermott et al. [ 1 ] in the paper identifying...
Articles
Articles
Clin Sci (Lond) (2015) 129 (5): 423–437.
Published: 11 June 2015
... apoptosis induced by a range of common stressors. Glucocorticoids, which are ubiquitously elevated for a prolonged period postoperatively, generated increased levels of mitochondrial reactive oxygen species, activated caspase-1 and mature interleukin (IL)-1β in human lymphocytes, suggesting inflammasome...
Includes: Supplementary data
Articles