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Keywords: inosine monophosphate dehydrogenase
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Mycophenolate mofetil, an inhibitor of inosine monophosphate dehydrogenase, causes a paradoxical elevation of GTP in erythrocytes of renal transplant patients

David GOLDSMITH, Elizabeth A. CARREY, Stephen EDBURY, Ryszard T. SMOLENSKI, Piotr. JAGODZINSKI, H. Anne SIMMONDS
Journal: Clinical Science
Clin Sci (Lond) (2004) 107 (1): 63–68.
https://doi.org/10.1042/CS20030331
Published: 23 June 2004
... lymphocyte IMPDH (inosine monophosphate dehydrogenase), thereby drastically decreasing GTP concentrations essential to lymphocyte proliferation in vitro and in vivo . Erythrocyte GTP concentrations are commonly elevated in severe renal disease, but normalize following successful engraftment. Consequently...
View article titled, Mycophenolate mofetil, an inhibitor of <span class="search-highlight">inosine</span> <span class="search-highlight">monophosphate</span> <span class="search-highlight">dehydrogenase</span>, causes a paradoxical elevation of GTP in erythrocytes of renal transplant patients
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