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Keywords: inotropic agents
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Clin Sci (Lond) (2001) 101 (6): 637–643.
Published: 20 November 2001
... atrium and the left ventricle. In conclusion, VIP has a direct positive inotropic effect in both the atria and the ventricles of the human heart. The presence of mRNAs for the VPAC 1 , VPAC 2 and PAC 1 receptors suggest that VIP may mediate its effect via these receptors. inotropic agents PAC1...
Clin Sci (Lond) (2000) 99 (6): 547–554.
Published: 23 November 2000
...Makoto KAWAI; John A. LEE; Clive H. ORCHARD We have investigated the effects of the calcium-sensitizing inotropic agent EMD 57033 on Ca 2+ handling in intact and skinned rat ventricular myocytes. Intracellular Ca 2+ was monitored using fura 2. Myocytes were saponin-skinned, allowing study of...
Clin Sci (Lond) (2000) 99 (3): 161–168.
Published: 02 August 2000
... ventricular level in the human heart. Correspondence : Dr Ole Saetrum Opgaard, Department of Pharmacology, College of Medicine, 360 Med Surge II, University of California, Irvine, CA 92697-4625, U.S.A. (e-mail osaetrum@uci.edu ). atrial function endothelins inotropic agents ventricular function...
Clin Sci (Lond) (1989) 76 (6): 609–618.
Published: 01 June 1989
...J. A. Lee; J. C. Ruegg; D. G. Allen 1. In this study we have investigated the effects of a novel inotropic agent, pimobendan (UDCG 115-BS), on skinned and intact ventricular muscle from ferrets. 2. Pimobendan (20 or 100 μmol/l) increased tension at a given free [Ca 2+ ] when applied to skinned...