...J. E. Clague; J. Carter; M. G. Pearson; P. M. A. Calverley 1. To examine the effects of sustained resistive loading on the relationship between inspiratory effort sensation and respiratory drive ( P 0.1) and to determine if the change in CO 2 responsiveness after sustained loading is accompanied...

...J. E. Clague; J. Carter; M. G. Pearson; P. M. A. Calverley 1. The physiological basis of inspiratory effort sensation remains uncertain. Previous studies have suggested that pleural pressure, rather than inspiratory muscle fatigue, is the principal determinant of inspiratory effort sensation...

...J. E. Clague; J. Carter; M. G. Pearson; P. M. A. Calverley 1. To examine the relationship between the inspiratory effort sensation (IES) and respiratory drive as reflected by mouth occlusion pressure ( P 0.1) we have studied loaded and unloaded ventilatory responses to CO 2 in 12 normal subjects. 2...