... to muscles to offset the supposed benefit of reduced body weight gain on insulin signalling in this major site for glucose tolerance (or insulin action). The study was conducted in mice exposed to chronic CS followed by either a chow (CH) diet or a high-fat (HF) diet. CS increased triglyceride (TG) levels...

...Michael L. Granda; Pooja Amarapurkar; Alessia Fornoni Clinical and experimental evidence support a cause–effect relationship between altered insulin signaling and development of kidney disease of metabolic and non-metabolic origin. However, the current criteria to measure and/or estimate...

... adipocyte adipokine fructose-rich diet insulin signalling lipid metabolism metabolic syndrome • The current epidemics of obesity, Type 2 diabetes and the MS could be ascribed to the drastic increase in fructose consumption. On the other hand, administration of an FRD to normal rats induces...

... on insulin sensitivity and endothelial function in hypertensive individuals with abdominal obesity and impaired fasting glucose. angiotensin II clinical trial hypertension insulin signalling obesity vascular function A fasting venous blood specimen was obtained at the initial visit...

... of isolated human subcutaneous fat arterioles; these effects were correlated with the expression of insulin signalling proteins. Periumbilical subcutaneous adipose tissue was explanted during surgery, small arterioles (internal diameter 220±40 μm) were dissected out and investigated by electron microscopy...