... ]. Cytokine Interleukin Pancreatic Pancreatic cancer is a devastating malignancy with a 5-year relative survival rate of only 3–9%, dependent on the geographical location surveyed [ 1–4 ], with these statistics exhibiting only modest improvement over the last four decades [ 1–3 ]. The median...

... reported in atherosclerosis and hypertension. Different subsets of lymphocytes and their cytokines are involved in vascular remodelling in hypertension, chronic kidney disease and heart disease. Effector T-cells include Th1 (interferon-γ-producing) and Th2 (interleukin-4 producing) lymphocytes, as well...

... DCPs), pDCPs (plasmacytoid DCPs), tDCPs (total DCPs) and serum levels of TNFα (tumour necrosis factor α), IL (interleukin)-2, -4, -5, -6, -10 and -12 were analysed by flow cytometry in blood of patients with NSTEMI [non-STEMI (ST-segment elevation myocardial infarction)] ( n =44) and STEMI ( n =34...

... injected with saline on day 0 (group E). Rats were killed on days 1, 3, 7 and 14. MSC prevented the increase in serum creatinine, proteinuria, glomerular monocyte influx and glomerular histopathological injury. Furthermore, MSC suppressed the release of IL-6 (interleukin-6) and TGF-β (transforming growth...

...) interleukin T-cell ulcerative colitis tumour necrosis factor (TNF) There is evidence that in IBDs, and particularly in CD, mucosal T-cell accumulation is partly dependent on a reduced rate of programmed cell death (apoptosis) [ 35 ]. The molecular mechanisms underlying this phenomenon are complex...

... level, and their activation status. Compared with ASD, inflammatory parameters associated with Th1-type [T-bet, IL (interleukin)-2, IFN-γ (interferon-γ), TNF-α (tumour necrosis factor-α), IL-1α and cytotoxic T-cells] and Th2-type [GATA3, IL-4, IL-10, IL-13 and B-cells] responses were all increased...

... have demonstrated that, in patients with Type 2 diabetes categorized into low (<1.0 mg/l), medium (1.0–3.0 mg/l) and high (>3.0 mg/l) hs-CRP groups, serum levels of hs-CRP correlated with lipopolysaccharide-stimulated release of interleukin-1β and interleukin-6 in whole blood. This finding may...

... pressure, body mass index, fasting blood glucose, glycated haemoglobin, cholesterol, triacylglycerols (triglycerides) and hs-CRP (high-sensitivity CRP) were measured. IL-6 (interleukin-6), IL-1β (interleukin-1β) and TNF-α (tumour necrosis factor-α) were measured before and after 24 h of incubation of whole...

... between the severity of early-onset overuse-related MSDs of the upper extremity and serum levels of IL-1β (interleukin-1β), TNF-α (tumour necrosis factor-α), IL-6 (interleukin-6) and CRP (C-reactive protein). Twenty-two subjects with upper-extremity MSDs due to overuse for no longer that 12 weeks were...

...Camille CHENEVIER-GOBEAUX; Séverine MORIN-ROBINET; Hervé LEMARECHAL; Serge POIRAUDEAU; Jean-Charles O. G. EKINDJIAN; Didier BORDERIE The aim of the present study was to investigate the effects of (i) the pro-inflammatory cytokines IL (interleukin)-1β, TNF-α (tumour necrosis factor-α), IFN-γ...

... studied within a 1.5-year period. Plasma levels of tumour necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6, IL-8 and endotoxin were determined on days 1, 4 and 7 after admission when hospital infection was suspected and 4 months later. A total of 24 patients (36.4%) were proven to be infected...

... that would distinguish SIRS patients with systemic inflammation from patients without inflammation. The study included 100 acutely ill patients with SIRS. Peripheral blood neutrophil and monocyte CD11b expression, serum interleukin-6, interleukin-1β, tumour necrosis factor-α and C-reactive protein were...

...Stephen J. WIGMORE; Jean P. MAINGAY; Kenneth C. H. FEARON; Michael G. O'RIORDAIN; James A. ROSS 1. This study investigates whether previously documented effects of interleukin-4 in down-regulating pro-inflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from healthy...

... of peptides and proteins which are involved in signalling between the cells of the immune system. Cytokines include interleukins (ILs), interferons, colony stimulating factors, tumour necrosis factors (TNFs) and transforming growth factors. A group- ing of three cytokines, IL-I, IL-6 and TNF-a, not only...