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Keywords: interleukin-1
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Articles
Clin Sci (Lond) (2021) 135 (17): 2035–2048.
Published: 31 August 2021
... interleukin-1 renin-angiotensin system Hypertension (HT) is one of the most important cause of deaths worldwide. Improved treatment strategies for HT, including antihypertensive agents, have increased survival rates. However, hypertensive patients with renal injury are at increased risk for death...
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Clin Sci (Lond) (2007) 112 (1): 1–25.
Published: 01 December 2006
... of the initiating event, the peripheral tissue macrophage can induce an inflammatory response through the release of the prototypical pro-inflammatory cytokines IL-1 (interleukin-1) β and TNF (tumour necrosis factor) α [ 1 ]. These cytokines act on endothelial cells to induce the expression of adhesion molecules...
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Clin Sci (Lond) (2002) 102 (4): 403–409.
Published: 05 March 2002
... gene expression in human osteoblast-like cells. The clinical relevance of our findings requires further investigation. bone metabolism fatty acids interleukin-1 macrophage colony-stimulating factor osteoblasts tumour necrosis factor-. Correspondence: Professor Bruno Baggio (e...
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Clin Sci (Lond) (1997) 92 (5): 519–525.
Published: 01 May 1997
... the effect of endotoxaemia and sepsis on brain interleukin-1 and interleukin-6 expression. 2. Male A/J mice were injected subcutaneously with lipopolysaccharide (10 mg/kg) or an equal volume of saline as control. Sepsis was induced by caecal ligation and puncture (CLP); control mice underwent sham-operation...
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Clin Sci (Lond) (1995) 88 (2): 211–217.
Published: 01 February 1995
... of interleukin 1, tumour necrosis factor and interleukin 6 were investigated in Kupffer cells derived from both young and old animals. 3. Basal production of biological response modifiers was low in cells of both young and old rats. Lipopolysaccharide stimulated production of the same types of monokines...
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Clin Sci (Lond) (1994) 86 (5): 619–626.
Published: 01 May 1994
... and histologically normal mucosa. 2. Addition of interleukin-1 stimulated release of greater quantities of all these inflammatory mediators, including interleukin-1 itself, from inflamed and normal mucosa. 3. Blockade of cyclo-oxygenase with indomethacin or of lipoxygenase with ICI 207968 or of phospholipase A 2...
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Clin Sci (Lond) (1992) 83 (4): 503–507.
Published: 01 October 1992
...Giulio Pioli; Guiseppina Basini; Mario Pedrazzoni; Giovanni Musetti; Vittorio Ulietti; Donatella Bresciani; Paola Villa; Alberto Bacchi; David Hughe; Graham Russell; Mario Passeri 1. We studied the changes in interleukin-1 and interleukin-6 secretion by peripheral blood mononuclear cells from 12...
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Clin Sci (Lond) (1991) 81 (5): 677–683.
Published: 01 November 1991
... capacity, per cent saturation of transferrin and serum ferritin level. 4. A significant increase in interleukin-1-type activity was demonstrated immediately and 24 h after exercise ( P <0.01). 5. It is concluded that the metabolic sequelae of sustained exercise are similar, but not analogous...
Articles
Clin Sci (Lond) (1989) 76 (5): 535–538.
Published: 01 May 1989
...-immunization. 3. The effect of rhIL-1β may be due, in part, to augmentation of the immune response to type II collagen. 4. Interleukin-1-accelerated, collagen-induced arthritis will provide a useful model for investigating the role of interleukin-1 in the regulation of arthritic diseases, and the development...
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Clin Sci (Lond) (1988) 75 (6): 561–567.
Published: 01 December 1988
...C. I. Westacott; J. T. Whicher; C. W. Hutton; P. A. Dieppe 1. Increased spontaneous production of interleukin-1, measured as lymphocyte-activating factor activity, was seen in unstimulated monocytes from systemic sclerosis patients. 2. Inhibitory activity to interleukin-1 was seen in both normal...
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Clin Sci (Lond) (1988) 75 (3): 251–255.
Published: 01 September 1988
...J. R. Weinberg; D. J. M. Wright; A. Guz 1. The cardiovascular effects of intravenous injections of interleukin-1 (IL-1) and tumour necrosis factor (TNF) have been investigated in the conscious rabbit. They have been compared with the effects of bacterial lipopolysaccharide (LPS) because both IL-1...
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