..., they underwent muscle sympathetic nerve activity (MSNA) analysis (microneurography), as well as ultrasensitive C-reactive protein (usCRP), interleukin-6 (IL-6), and lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) activity measurements. These evaluations were repeated at 1, 3, and 6 months after...

... on small intestinal barrier function in humans. Here, their findings are briefly summarised and the wider implications discussed. aging gut permeability immunosenescence interleukin-6 intestine The mammalian intestine contains a huge burden of commensal micro-organisms which in the lumen...

... in nature or endogenous RNA from necrotic cells. Correspondence: Dr Steven O’Reilly (email steven.o’reilly@newcastle.ac.uk ). 5 7 2013 22 8 2013 27 8 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 fibrosis innate immune system interleukin-6...

...Cedric Hubeau; John E. Kubera; Katherine Masek-Hammerman; Cara M. M. Williams Increased systemic and pulmonary levels of IL-6 (interleukin-6) are associated with the severity of exacerbations and decline of lung function in patients with COPD (chronic obstructive pulmonary disease). Whether IL-6...

... (determined by ultrasound), S I (insulin sensitivity index; determined by isoglycaemic–hyperinsulinaemic clamp) and serum levels of CRP (C-reactive protein), TNF-α (tumour necrosis factor-α), IL-6 (interleukin 6), resistin and adiponectin (determined by ELISA) were measured. Associations between FMD/NTG and S...

... 5 2002 12 7 2002 The Biochemical Society and the Medical Research Society © 2002 2002 acetylcholine cytokine endothelial function endothelin-1 (ET-1) interleukin-6 sodium nitroprusside tumour necrosis factor (TNF-α). 409Clinical Science (2002) 103, 409 415 (Printed...

... protein-1 antibiotics ciprofloxacin interleukin-6 interleukin-8 nuclear factor B nuclear factor IL-6 405Clinical Science (2000) 99, 405 410 (Printed in Great Britain) Effect of ciprofloxacin on the activation of the transcription factors nuclear factor jB, activator protein-1 and nuclear factor...

..., and serum levels of interleukin-6, soluble interleukin-6 receptor and the soluble tumour necrosis factor receptors in patients with pancreatic cancer. Thirty-four blood samples were collected from 13 patients with advanced pancreatic cancer. Samples were also collected from six healthy subjects. Levels of C...

... the effect of endotoxaemia and sepsis on brain interleukin-1 and interleukin-6 expression. 2. Male A/J mice were injected subcutaneously with lipopolysaccharide (10 mg/kg) or an equal volume of saline as control. Sepsis was induced by caecal ligation and puncture (CLP); control mice underwent sham-operation...

... eicosapentaenoic acid compared with 0.8 ± 0.8 mg/l after 4 weeks of eicosapentaenoic acid, P < 0.05), but no significant reduction in the serum concentration of the hepatocyte-stimulating cytokine interleukin-6. Production of interleukin-6 by peripheral blood mononuclear cells isolated from patients...

... as well as the activities and mRNA levels of proteasomes (26S and 20S) and cathepsins (B, L, and H) were examined in the presence of various amounts of cytokines. 2. It was found that 100 units/ml recombinant human interleukin-6 somewhat shortened the half-life of long-lived proteins to 23.79 ± 1.55 h...

... necrosis factor production, plasma interleukin-6 and acute-phase protein concentration and antioxidant vitamins in smokers and non-smokers. 2. Measurement of tumour necrosis factor was conducted in whole blood stimulated with endotoxin (lipopolysaccharide), and interleukin-6 concentrations were measured...

... of interleukin 1, tumour necrosis factor and interleukin 6 were investigated in Kupffer cells derived from both young and old animals. 3. Basal production of biological response modifiers was low in cells of both young and old rats. Lipopolysaccharide stimulated production of the same types of monokines...

... and butter for 4 and 8 weeks on subsequent cytokine production by peritoneal macrophages of rats. 4. Tumour necrosis factor production in response to a lipopolysaccharide stimulus and interleukin-1 and interleukin-6 production in response to a tumour necrosis factor challenge were studied. 5. All fats...

... body composition human immunodeficiency virus interleukin-6 malnutrition nutritional status prognosis soluble tumour necrosis factor receptors tumour necrosis factor wasting Clinical Science (1994) 86, 461467 (Printed in Great Britain) 461 Tumour necrosis factor receptor levels are linked...

...J. F. Doherty; M. H. N. Golden; D. G. Remick; G. E. Griffin 1. Cytokine production in vitro was assessed in 16 malnourished children, before and after nutritional recovery. 2. Tumour necrosis factor-α and interleukin-6 were measured in whole blood after lipopolysaccharide stimulation. 3. The total...

...R. J. D'Souza; H. M. Phillips; P. W. Jones; R. C. Strange; G. M. Aber 1. This study examined the influence of H 2 O 2 , interleukin-6 and platelet-derived growth factor on the proliferation of rat mesangial cells. Mesangial cells were exposed to either a single pulse or three daily pulses of H 2 O...

... were obtained at timed intervals (0–14 days) after the injection for determination of albumin, total protein, α 2 -macroglobulin (a major acute-phase protein in the rat) and interleukin-6 concentrations. The magnitude and pattern of the acute-phase protein response was then compared with the local...

...Giulio Pioli; Guiseppina Basini; Mario Pedrazzoni; Giovanni Musetti; Vittorio Ulietti; Donatella Bresciani; Paola Villa; Alberto Bacchi; David Hughe; Graham Russell; Mario Passeri 1. We studied the changes in interleukin-1 and interleukin-6 secretion by peripheral blood mononuclear cells from 12...

... peptide-1/interleukin-8 may be of specific functional importance in mediating inflammation in ulcerative colitis. 4 9 1991 8 10 1991 © 1992 The Biochemical Society and the Medical Research Society 1992 Crohn's disease cytokines inflammatory bowel disease interleukin-6...

...A. M. Cruickshank; W. D. Fraser; H. J. G. Burns; J. Van Damme; A. Shenkin 1. Recent studies have suggested that interleukin-6 is a major mediator of the acute-phase protein response in man. The aim of the present study was to investigate the relationships between the response of serum interleukin-6...