...Garry Tew; Shah Nawaz; Irena Zwierska; John M. Saxton Arm cranking is a useful alternative exercise modality for improving walking performance in patients with intermittent claudication; however, the mechanisms of such an improvement are poorly understood. The main aim of the present study...

...), is an adaptation to a chronic mismatch between oxygen demand and supply. Patients with IC (intermittent claudication) experience pain during exercise associated with an inadequate oxygen delivery to the muscles. Therefore the aims of the present study were to examine the plasma VEGF response to acute exercise...

...Glenn A. BARKER; Simon GREEN; Anita A. GREEN; Philip J. WALKER In the present study, we tested the hypothesis that walking intolerance in intermittent claudication (IC) is related to both slowed whole body oxygen uptake ( V O 2 ) kinetics and altered activity of the active fraction of the pyruvate...

... tolerance, we investigated plasma levels of VEGF in 50 patients with intermittent claudication who were allocated randomly to groups receiving cilostazol ( n = 17), pentoxifylline ( n = 17) or placebo ( n = 16). Patients given either cilostazol or pentoxifylline showed a significant improvements in maximal...

... with intermittent claudication ( n = 38) and controls ( n = 20). The activities of CS, ACDH and Cyt-ox were increased and the activity of Cyt-ox was positively correlated to the maximal walking distance (MWD) in the patients. 2. Thirty-three patients with intermittent claudication were randomized to three treatment...

... most probably originates in type II fibres. 24 2 1982 31 3 1982 © 1982 The Biochemical Society and the Medical Research Society 1982 blood flow exercise gastrocnemius intermittent claudication muscle fibres soleus Clinical Science (1982) 63,293-299 29 3 Metabolic response...