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Keywords: ion channels
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Articles
Clin Sci (Lond) (2021) 135 (21): 2521–2540.
Published: 09 November 2021
... transport involved in the development of PKDs ( A ) In ADPKD : Loss of PC1 and/or PC2 function as well as abnormal activities of other Ca 2+ -permeable ion channels (e.g. PC1/PC2, TRPC1/PC2, TRPV4/PC2, IP3/PC2, RyR/PC2 complexes in the primary cilium or the ER) alter intracellular Ca 2+ influx, which...
Articles
Clin Sci (Lond) (2018) 132 (2): 173–183.
Published: 19 January 2018
... of many classes of renal ion channels, including those that transport Na + (ENaC), K + (ROMK/BK), Ca 2+ (TRPV4/5/6), Mg 2+ (TRPM7/6), and Cl − (ClC-K, CFTR). Here, we discuss the mechanisms by which ASDN expressed channels are up-regulated by SGK1, while highlighting newly discovered pathways connecting...
Articles
Clin Sci (Lond) (2016) 130 (10): 747–759.
Published: 01 April 2016
... and lengthening of the QT interval. There is an increased susceptibility to arrhythmias during pregnancy and the postpartum period. Some changes in the ECG are clearly the result of changes in ion channel expression and behaviour, but little is known about the ionic basis for this electrical remodelling. Most...
Articles
Clin Sci (Lond) (2005) 109 (3): 267–276.
Published: 24 August 2005
... effects on the interaction between platelets and neutrophils. Correspondence: Professor Nen-Chung Chang (email [email protected] ). 31 1 2005 8 4 2005 18 5 2005 18 5 2005 The Biochemical Society 2005 angioplasty coronary disease inflammation ion channels...
Articles
Clin Sci (Lond) (2003) 104 (1): 39–46.
Published: 16 December 2002
... and the calibre of re- sistance vessels. In skeletal muscle, as in the myocardium, blood flow is closely linked to metabolic rate. During exercise, the changing metabolic demands are closely matched by concomitant changes in blood flow, allowing Key words : ion channels, microcirculation, regional blood flow...
Articles
Articles
Clin Sci (Lond) (1985) 68 (5): 517–521.
Published: 01 May 1985
... of adrenaline on coupled active transport of ions is mediated by β 2 -adrenoceptors. 26 11 1984 18 12 1984 © 1985 The Biochemical Society and the Medical Research Society 1985 adenosine triphosphatase β-adrenoceptors catecholamines hypokalaemia ion channels leucocytes potassium...