... Commons Attribution License 4.0 (CC BY-NC-ND) . Electrolyte transport Ion channels Kidney Polycystic Kidney Disease purinergic signaling Renal Physiology Polycystic kidney disease (PKD) is a group of inherited nephropathies characterized by the formation of fluid-filled sacs along...

... of many classes of renal ion channels, including those that transport Na + (ENaC), K + (ROMK/BK), Ca 2+ (TRPV4/5/6), Mg 2+ (TRPM7/6), and Cl − (ClC-K, CFTR). Here, we discuss the mechanisms by which ASDN expressed channels are up-regulated by SGK1, while highlighting newly discovered pathways connecting...

... and lengthening of the QT interval. There is an increased susceptibility to arrhythmias during pregnancy and the postpartum period. Some changes in the ECG are clearly the result of changes in ion channel expression and behaviour, but little is known about the ionic basis for this electrical remodelling. Most...

... effects on the interaction between platelets and neutrophils. Correspondence: Professor Nen-Chung Chang (email ncchang@tmu.edu.tw ). 31 1 2005 8 4 2005 18 5 2005 18 5 2005 The Biochemical Society 2005 angioplasty coronary disease inflammation ion channels...

... and the calibre of re- sistance vessels. In skeletal muscle, as in the myocardium, blood flow is closely linked to metabolic rate. During exercise, the changing metabolic demands are closely matched by concomitant changes in blood flow, allowing Key words : ion channels, microcirculation, regional blood flow...

... with hyperpolarization of chondrocyte cell membranes and activation of Ca 2+ -dependent K + -ion channels but the physiological basis for this response to mechanical stimulation is unclear. 2. Experiments have been undertaken to better define the types of ion channels involved and to explore the possibility...

... of adrenaline on coupled active transport of ions is mediated by β 2 -adrenoceptors. adenosine triphosphatase β-adrenoceptors catecholamines hypokalaemia ion channels leucocytes potassium sodium 26 11 1984 18 12 1984 © 1985 The Biochemical Society and the Medical Research Society...