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Keywords: kallikreins
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Articles
Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice
Open AccessCorey S. Moran, Sai-Wang Seto, Erik Biros, Smriti M. Krishna, Susan K. Morton, Christoph Kleinschnitz, Con Panousis, Jonathan Golledge
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (9): 1049–1061.
Published: 04 May 2020
... in AAA pathogenesis. Kinins are bioactive peptides important in regulating inflammation. Stimulation of the kinin B2 receptor has been previously reported to promote AAA development and rupture in a mouse model. The endogenous B2 receptor agonist, bradykinin, is generated from the kallikrein–kinin system...
Includes: Supplementary data
