...A. J. A. Al-Modhefer; M. W. B. Bradbury; T. J. B. Simons 1. The binding of lead to human blood serum, and components of serum, was studied by titration with the addition of Pb(NO 3 ) 2 solution, monitoring the free Pb 2+ concentration with a Pb 2+ electrode, and by equilibrium dialysis. 2. In fresh...

...Elmar Weiler; Farhad Khalil-Manesh; Harvey C. Gonick 1. Lead, ouabain and an endogenous plasma inhibitor were all found to be potent inhibitors of purified hog cerebral cortex sodium—potassium-activated adenosine triphosphatase and potassium-stimulated p -nitrophenylphosphatase. 2. The kinetic...

...M. J. Henderson; C. Toothill 1. Lead acetate was administered to adult New Zealand White rabbits in their drinking water. Their mean blood lead level rose to 4.5 μmol/l within a week and then remained relatively constant. 2. The rabbits developed a marked coproporphyrinuria. Plasma levels...

...P. A. Meredith; M. R. Moore; A. Goldberg 1. The activity of erythrocyte δ-aminolaevulinic acid (ALA) dehydratase and blood protoporphyrin concentrations have been measured in patients with various anaemias, a group of subjects with known lead exposure and a group of control subjects. Leucocyte ALA...

...M. R. Moore; P. A. Meredith; A. Goldberg; K. E. Carr; P. G. Toner; T. D. V. Lawrie 1. There is no known cause for the increased mortality due to ischaemic heart disease in soft water areas. Since the lead concentration of soft water is elevated in houses with lead plumbing, studies have been...

...J. K. Howard 1. Blood lead and erythrocyte glutathione reductase (GSSG-R) and glucose 6-phosphate dehydrogenase (G6P-D) activities were measured in normal subjects and in those with occupational exposure to lead. 2. With increasing blood lead concentration, GSSG-R activity increases and that of G6P...