...Sammy W. M. Shiu; Su-Mei Xiao; Ying Wong; Wing-Sun Chow; Karen S. L. Lam; Kathryn C.B. Tan LDL (low-density lipoprotein) is subjected to pro-atherogenic modifications in the circulation. A novel uraemia-independent mechanism of carbamylation of lipoproteins mediated by MPO (myeloperoxidase) has...

..., age is an independent non-modifiable risk factor and the predictive power of age far outweighs that of the other risk factors. In the causal exposure model, age is the duration of time the arterial wall is exposed to the causes of atherosclerosis: apoB (apolipoprotein B) lipoproteins, hypertension...

... studies also indicate that cardiovascular risk factors, including elevated blood cholesterol and triacylglycerol (triglyceride), increase the likelihood of AD and vascular dementia. Lipids and lipoproteins in the circulation interact intimately with the cerebrovasculature, and may have important effects...

...Sanjeev Sirpal There is an emerging and significant body of research that suggests that MPO (myeloperoxidase) may be a critical mediator in dysfunctional lipoprotein formation and, hence, atherogenic initiation and progression. MPO is a haem peroxidase found in leucocytes and is abundant...

...Allan D. Sniderman; Jean-Charles Hogue; Jean Bergeron; Claude Gagné; Patrick Couture On the basis of a high correlation, non-HDL-C (non-high-density lipoprotein cholesterol) and apoB (apolipoprotein B) have been suggested to be of equivalent value for clinical practice; however, the strength...

...) hypertriglyceridaemia lipid phenotype lipoprotein liver steatosis Knowing the sequence of our genes does not automatically mean we know how they cause vascular disease. To be sure, in a few monogenic disorders, such as FH (familial hypercholesterolaemia), there is a simple short straight line between genetic...

.... Additionally, the association of ALT with the switch in triacylglycerol phenotype suggests a central role of the liver in the pathogenesis of FCHL. The hypertriglyceridaemic phenotype in FCHL is the consequence of both an excessive production of VLDL (very-low-density lipoprotein) particles and an impaired...

... and placebo. The net change of total cholesterol or LDL (low-density lipoprotein)-cholesterol was not associated with the net change in FMD when the study group was considered as a whole or the smoking group was considered separately. In conclusion, improved endothelial function was observed in a group...

.... diabetes lipid lipoprotein macrosomia polyunsaturated fatty acid pregnancy Maternal diabetes during pregnancy is an important risk factor for fetal overnutrition leading to fetal obesity or macrosomia, resulting from the combined effects of excessive transfer of maternal nutrients...

... the inferior margin of the last rib and the crest of the ilium in the horizontal plane whilst in an upright position. After a 12-h fast, serum glucose, total cholesterol, triacylglycerol (triglyceride) and HDL-C (high-density lipoprotein cholesterol) concentrations were determined using an autoanalyser (747...

... associated with macrosomia. Correspondence: Dr Naim A. Khan (e-mail [email protected] ). 22 4 2003 6 8 2003 7 8 2003 7 8 2003 © 2003 The Biochemical Society 2003 diabetes lipoprotein macrosomia polyunsaturated fatty acid (PUFA) Clinical Science (2003) 105...

...Fernando D. BRITES; Pablo A. EVELSON; Marina García CHRISTIANSEN; María F. NICOL; María José BASÍLICO; Regina W. WIKINSKI; Susana F. LLESUY Physical activity is known to induce oxidative stress in individuals subjected to intense exercise. In this study, we investigated the lipoprotein profile...

...Massimino Carrella; Annalisa Csillaghy; Renato de Mercato; Agesilao D'Arienzo 1. Chylomicron remnants, the intermediate intestinal lipoproteins carrying the bulk of dietary cholesterol, are actively taken up and degraded in the hepatocytes, releasing cholesterol which can be excreted in bile...

... to pre-very low density lipoprotein (VLDL) particles. 4. Studies on biopsies from patients with alcoholic fatty liver showed a 2–3-fold increase in triglyceride in both lipid droplet fractions but most of the accumulating triglyceride was sedimentable and membrane-bound. 5. Needle biopsy specimens from...

...R. S. Elkeles; S. R. Khan; V. Chowdhury; M. B. Swallow 1. Changes in serum triglyceride and high density lipoprotein (HDL) cholesterol after a fatty meal have been studied in smokers and non-smokers. 2. Average serum triglyceride during the study was higher in smokers than in non-smokers. 3. In non...

...V. J. Wass; R. J. Jarrett; V. Meilton; M. K. Start; M. Mattock; C. S. Ogg; J. S. Cameron 1. Changes in serum total and lipoprotein fraction triglyceride and cholesterol levels were studied in 24 adults on home haemodialysis. Half the patients were randomly allocated to a low cholesterol (mean 200...

...-esterified cholesterol of very-low-density lipoprotein (VLDL) had risen by a mean of 0.09 mmol/l (43% increase, P < 0.001), that of the esterified cholesterol of VLDL had risen by a mean of 0.11 mmol/l (38% increase, P < 0.01), and that of the triglyceride of VLDL had risen by a mean of 0.40 mmol/l (53...

...G. R. Thompson; J. Heath; M. Press 1. The fatty acid composition of the cholesterol esters, triglycerides and lecithin components of the major plasma lipoprotein classes was determined before and after the intravenous infusion of a linoleate preparation into a patient with essential fatty acid...

... lipoprotein triglyceride. 2. Plasma FFA equilibrates reversibly with the interstitial lymph. This makes it necessary to use either a pulse injection, with analysis of the results in terms of a two-compartment model, or continuous infusion of the label in determining the FFA flux. 3. The recycling of labelled...

...Gilbert R. Thompson; J. Paul Miller 1. Plasma lipids and lipoproteins have been studied in control subjects and patients with various types of steatorrhoea. 2. Low plasma cholesterol levels were found in malabsorbers and were associated with decreased amounts of low-density lipoprotein (LDL...