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1-29 of 29
Keywords: lipoproteins
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Articles
Circulating miR-33a and miR-33b are up-regulated in familial hypercholesterolaemia in paediatric age
Francesco Martino, Fabrizio Carlomosti, Daniele Avitabile, Luca Persico, Mario Picozza, Francesco Barillà, Marcello Arca, Anna Montali, Eliana Martino, Cristina Zanoni, Sandro Parrotto, Alessandra Magenta
Journal:
Clinical Science
Clin Sci (Lond) (2015) 129 (11): 963–972.
Published: 10 September 2015
... control, therefore, together with atherogenic factors, they can stimulate atherosclerotic degeneration of the vessel walls of arteries. miR-33a and miR-33b play a pivotal role in a variety of biological processes including cholesterol homoeostasis, HDL (high-density lipoprotein)-cholesterol formation...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (5): 451–460.
Published: 03 October 2002
..., Royston, Herts. SG8 5HD, U.K. 13 3 2002 25 6 2002 24 7 2002 atherosclerosis endothelial function lipoproteins nitric oxide vasoconstriction/dilation 451Clinical Science (2002) 103, 451 460 (Printed in Great Britain) Chylomicron-remnant-like particles inhibit receptor...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (6): 697–706.
Published: 15 November 1999
...A. BARDEN; L. J. BEILIN; K. BOTH; J. RITCHIE; P. LEEDMAN; B. N. WALTERS; C. A. MICHAEL In order to evaluate whether lipid abnormalities may contribute to endothelial dysfunction in pre-eclampsia, the present study examined the in vitro effects of very-low-density lipoprotein (VLDL), low-density...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (2): 175–181.
Published: 18 June 1999
...Duo LI; Madeleine BALL; Melinda BARTLETT; Andrew SINCLAIR In the present study we investigated serum lipoprotein(a) [Lp(a)] levels, plasma lipids, the serum phospholipid polyunsaturated fatty acid profile and correlates of serum Lp(a) in healthy free-living female vegetarians ( n = 50...
Articles
Pascale Richard, Isabelle Beucler, Maria Pascual De Zulueta, Nicolas Biteau, Jean-Luc De Gennes, Albert Iron
Journal:
Clinical Science
Clin Sci (Lond) (1997) 93 (1): 89–95.
Published: 01 July 1997
... at the age of 10. 3. The exploration of apoE status associated with plasma lipid levels and lipoprotein profiles in this three-generation pedigree made it possible to describe a compound heterozygote for two mutated alleles, one mutation being located in the N-terminal domain of the apoE protein...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1997) 92 (5): 473–479.
Published: 01 May 1997
...-density lipoprotein and high-density lipoprotein on blood viscosity correlate with their association with risk of atherosclerosis. 2. Blood viscometry was performed on samples from 28 healthy, non-fasting adult volunteers using a capillary viscometer. Data were correlated with haematocrit, fibrinogen...
Articles
Richard H. Neary, Mark D. Kilby, Padma Kumpatula, Francis L. Game, Deepak Bhatnagar, Paul N. Durrington, P. M. Shaughn O'Brien
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (3): 311–318.
Published: 01 March 1995
... to establish whether the placenta has a role in feto-maternal cholesterol metabolism through either synthesis or transplacental cholesterol flux. The potential for free cholesterol diffusion between mother and fetus and rates of cholesterol esterification and transfer between lipoproteins were determined...
Articles
Shui-Ping Zhao, Arn M. J. M. Van den Maagdenberg, Ton F. F. P. Vroom, Ferdinand M. Van't Hooft, Jan A. Gevers Leuven, Louis M. Havekes, Rune R. Frants, Arnoud Van Der Laarse, Augustinus H. M. Smelt
Journal:
Clinical Science
Clin Sci (Lond) (1994) 86 (3): 323–329.
Published: 01 March 1994
...Shui-Ping Zhao; Arn M. J. M. Van den Maagdenberg; Ton F. F. P. Vroom; Ferdinand M. Van't Hooft; Jan A. Gevers Leuven; Louis M. Havekes; Rune R. Frants; Arnoud Van Der Laarse; Augustinus H. M. Smelt 1. The plasma lipoprotein profiles of eight members of a Dutch pedigree spanning three generations...
Articles
D. J. Stensel, A. E. Hardman, K. Brooke-Wavell, D. Vallance, P. R. M. Jones, N. G. Norgan, A. F. Winder
Journal:
Clinical Science
Clin Sci (Lond) (1993) 85 (6): 701–708.
Published: 01 December 1993
...D. J. Stensel; A. E. Hardman; K. Brooke-Wavell; D. Vallance; P. R. M. Jones; N. G. Norgan; A. F. Winder 1. The purpose of this study was to examine the influence of brisk walking on serum lipoprotein variables. 2. Seventy-two apparently healthy but physically inactive men (aged 42–59 years) were...
Articles
Robert A. Hegele, George Zahariadis, Alexandra L. Jenkins, Philip W. Connelly, Hanoch Kashtan, Hartley Stern, Robert Bruce, David J. A. Jenkins
Journal:
Clinical Science
Clin Sci (Lond) (1993) 85 (3): 269–275.
Published: 01 September 1993
... apolipoprotein B-containing lipoprotein concentrations to increases in dietary fibre. 2. We studied 67 subjects (43 men and 24 women) who had taken part in parallel 2 week metabolic dietary studies involving either wheat bran or oat bran supplementation. Fasting blood lipid, lipoprotein and apolipoprotein...
Articles
C. A. Abbott, M. I. MacKness, S. Kumar, A. O. Olukoga, C. Gordon, S. Arrol, D. Bhatnagar, A. J. M. Boulton, P. N. Durrington
Journal:
Clinical Science
Clin Sci (Lond) (1993) 85 (1): 77–81.
Published: 01 July 1993
... in the normal range. 6. These results are consistent with the view that butyrylcholinesterase may have a role in the altered lipoprotein metabolism in hypertriglyceridaemia associated with insulin insensitivity or insulin deficiency in diabetes mellitus. 24 3 1993 6 4 1993 © 1993...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 83 (3): 353–356.
Published: 01 September 1992
.... The plasma and erythrocyte cholesterol-to-phospholipid molar ratios remained closely correlated ( r = 0.77, P <0.01) before and after treatment, suggesting that S -adenosyl- l -methionine had not acted directly on the cells but rather had improved their lipoprotein milieu. Further support for this concept...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (5): 535–541.
Published: 01 May 1992
... acetylhydrolase activity and serum total cholesterol and low-density-lipoprotein-cholesterol concentrations in both subject groups. Although acetylhydrolase activity was most closely associated with the low-density-lipoprotein-cholesterol fraction, the activity for a given serum level of low-density-lipoprotein...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (1): 1–8.
Published: 01 January 1992
...Keith N. Frayn; Simon W. Coppack © 1992 The Biochemical Society and the Medical Research Society 1992 adipose tissue coronary heart disease insulin insulin resistance lipoproteins non-esterified fatty acids triacylglycerol Clinical Science (1992) 82, 1-8 (Printed in Great Britain...
Articles
Peter H. Winocour, Paul N. Durrington, Monica Ishola, Chris Gordon, Julie Jeacock, David C. Anderson
Journal:
Clinical Science
Clin Sci (Lond) (1989) 77 (4): 369–374.
Published: 01 October 1989
...). Its role in lipid metabolism in IDDM is not clearly defined. We examined the relationships between serum lipid and lipoprotein concentrations and the response of circulating C-peptide to a test meal in 205 subjects with IDDM. 2. Lipid and lipoprotein levels and glycaemic control did not differ...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (5): 549–556.
Published: 01 May 1987
...Robin J. Northcote; David Ballantyne 1. β-Adrenoceptor blocker therapy is known to cause disturbances of the lipoprotein profile. The long-term effects of β-adrenoceptor blockers and the influence of intrinsic sympathomimetic activity (ISA) has not been clearly defined. We measured serum...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (5): 581–587.
Published: 01 May 1985
...M. Boberg; L. B. Croon; I.-B. Gustafsson; B. Vessby 1. The fatty acid composition in platelet phospholipids and in the plasma lipid esters as well as the serum lipoprotein lipid concentrations were determined in 67 healthy male subjects in order to establish the relationships between blood lipids...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (6): 637–642.
Published: 01 June 1983
... lipoprotein-cholesterol levels decreased markedly, but pre-exchange levels were not achieved within 2 weeks. High density lipoprotein-cholesterol and apolipoprotein A-I levels also fell but returned to the original concentration after only 5 days. 2. Platelet aggregation and [ 14 C]serotonin release were...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 62 (2): 125–129.
Published: 01 February 1982
...J. P. D. Reckless; J. Stocks; G. Holdsworth © 1982 The Biochemical Society and the Medical Research Society 1982 apolipoproteins C-apoproteins. high-density lipoproteins hypertriglyceridaemia lipoproteins triglyceride-rich lipoproteins. very-low-density lipoproteins Clinical Science...
Articles
Studies of a Variant Very-Low-Density Lipoprotein with an Acquired Deficiency of Apolipoprotein C-II
Journal:
Clinical Science
Clin Sci (Lond) (1982) 62 (1): 93–100.
Published: 01 January 1982
...J. P. D. Reckless; J. Stocks; G. Holdsworth; D. J. Galton; A. J. Suggett; K. W. Walton 1. A variant very-low-density lipoprotein was associated with severe hypertriglyceridaemia. Urea—polyacrylamide gel electrophoresis of the tetramethylurea-soluble apolipoproteins of these very-low-density...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 437s–439s.
Published: 01 December 1981
...A. Meier; H. Schiffl; P. Weidmann; R. Mordasini; W. Riesen; C. Bachmann 1. The effect of treatment with a thiazide-like diuretic alone or combined with a β-adrenoceptor blocker on serum lipoproteins was investigated in 35 patients with essential hypertension. 2. In group I (18 patients), serum low...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (5): 649–651.
Published: 01 November 1981
...R. F. Heller; N. E. Miller; B. Lewis; A. Vermeulen; Angela Fairney; V. H. T. James; A. V. Swan 1. A study of 150 middle-aged male industrial employees has shown significant positive correlations between plasma levels of high-density-lipoprotein (HDL) cholesterol and both serum testosterone...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (2): 129–133.
Published: 01 August 1981
...D. N. Brindley © 1981 The Biochemical Society and the Medical Research Society 1981 atherosclerosis diabetes diet ethanol fatty liver fructose glucocorticoids insulin lipid metabolism lipoprotein lipase lipoproteins obesity l-α-phosphatidate phosphohydrolase sorbitol stress...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 58 (5): 419–421.
Published: 01 May 1980
...C. H. Bolton; LYN Jackson; C. J. C. Roberts; M. Hartog 1. Serum and lipoprotein cholesterol and triglycerides were measured before, during and after the administration of glutethimide (500 mg daily) for 21 days to six healthy volunteer subjects. 2. Evidence of enzyme induction was provided...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 109s–110s.
Published: 01 December 1979
..., after a change in the tertiary structure, to the plasma protease inhibitors α 2 -macroglobulin, inter-α-trypsin inhibitor and α 2 -antithrombin. It binds also to lipoprotein and an unidentified plasma protein. No binding was seen to more than 50 other studied plasma proteins. 6. The high-molecular...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1979) 56 (1): 71–76.
Published: 01 January 1979
...G. D. Calvert; H. M. James 1. We studied the turnover of low-density lipoprotein, density 1·031–1·056 kg/l, in five normal subjects and in four subjects with hyperlipoproteinaemia, using as tracer low-density lipoprotein labelled in the protein moiety with 131 I. We analysed data derived...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1977) 52 (1): 75–82.
Published: 01 January 1977
...J. Green; S. Carney 1. Electrophoresis of pre-stained lipoproteins on acrylamide-gel gradients has been carried out on serum from populations of control subjects and patients with ischaemic heart disease. The technique resolves components intermediate in position and, by inference, in size, between...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1975) 49 (6): 617–620.
Published: 01 December 1975
... that there was a reduction of plasma lecithin—cholesterol acyltransferase activity as well as decreased ability of the lipoprotein substrates of the enzyme to support esterification. 3. On this diet, there was no change in the proportion of the plasma cholesterol esterified but the plasma cholesterol and triglyceride...
Articles
Observations on the Passage of Apoproteins from Plasma Lipoproteins into Peripheral Lymph in Two Men
Journal:
Clinical Science
Clin Sci Mol Med (1975) 49 (5): 419–426.
Published: 01 November 1975
...D. Reichl; A. Postiglione; N. B. Myant; J. J. Pflug; M. Press 1. The passage of radioactive apolipoproteins into lymph draining the foot was investigated in two men, each given a single intravenous injection of low-density lipoprotein containing 131 I-labelled apoprotein B and of very-low-density...
