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Keywords: liposomes
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Articles

Tissue and Hepatic Subcellular Distribution of Liposomes Containing Bleomycin after Intravenous Administration to Patients with Neoplasms

A. W. Segal, G. Gregoriadis, J. P. Lavender, D. Tarin, T. J. Peters
Journal: Clinical Science
Clin Sci Mol Med (1976) 51 (4): 421–425.
https://doi.org/10.1042/cs0510421
Published: 01 October 1976
...A. W. Segal; G. Gregoriadis; J. P. Lavender; D. Tarin; T. J. Peters 1. Liposomes containing 111 In-labelled bleomycin were injected intravenously into two patients. One patient had a hepatoma and the other had secondary adenocarcinomatous deposits in the liver. 2. The tissue distribution of 111...
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Articles

Liposomes as Vehicles for the Local Release of Drugs

A. W. Segal, G. Gregoriadis, C. D. V. Black
Journal: Clinical Science
Clin Sci Mol Med (1975) 49 (2): 99–106.
https://doi.org/10.1042/cs0490099
Published: 01 August 1975
...A. W. Segal; G. Gregoriadis; C. D. V. Black 1. The rat testicle was used in studying the release of radio-labelled compounds from locally injected liposomes of various sizes, charge and lipid composition. 2. Large unsonicated liposomes markedly delayed the release of entrapped 125 I-labelled...
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