... ligation to induce liver cirrhosis and/or portal hypertension. The impacts of acute or chronic changes in environmental temperature were surveyed. The results showed that acute cooling from 25 to 15°C and 5°C increased the portal pressure by 10.6% and 15.5% in cirrhotic rats, and by 22.2% and 36.1...

...Shao-Jung Hsu; Ming-Hung Tsai; Ching-Chih Chang; Yu-Hsin Hsieh; Hui-Chun Huang; Fa-Yauh Lee; Chiao-Ling Chuang; Ming-Chih Hou; Shou-Dong Lee Liver cirrhosis is characterized by portal hypertension. However, the alteration of portal hypertension-related derangements during cirrhosis resolution...

...Hung-Chun Tung; Shao-Jung Hsu; Ming-Hung Tsai; Te-Yueh Lin; I-Fang Hsin; Te-Ia Huo; Fa-Yauh Lee; Hui-Chun Huang; Hsin-Ling Ho; Han-Chieh Lin; Shou-Dong Lee In liver cirrhosis, the altered levels of vasoactive substances, especially endothelin-1 (ET-1) and nitric oxide (NO) lead to elevated...

... of rosuvastatin therapy on HPS may be through, at least in part, dual pathways of anti-inflammation by inhibition of TNF-α/NF-κB/iNOS and anti-angiogenesis by attenuations of VEGF/VEGFR-1,2/Rho-A kinase. hepatopulmonary syndrome inflammatory angiogenesis liver cirrhosis rosuvastatin • HPS...

...Shao-Jung Hsu; Sun-Sang Wang; I-Fang Hsin; Fa-Yauh Lee; Hui-Chun Huang; Teh-Ia Huo; Wen-Shin Lee; Han-Chieh Lin; Shou-Dong Lee Abnormal angiogenesis in liver cirrhosis often leads to severe complications such as variceal haemorrhage and encephalopathy. Furthermore, splanchnic angiogenesis elevates...

... Journal compilation © 2014 Biochemical Society 2014 (−)-epigallocatechin-3-gallate (EGCG) angiogenesis green tea polyphenol (GTP) liver cirrhosis portosystemic collateral Cirrhosis, and its main complication PH (portal hypertension), represents a leading cause of mortality worldwide...

... intrapulmonary shunt liver cirrhosis sorafenib • HPS is characterized by oxygen desaturation in patients with chronic liver disease. The initiation of HPS arises from abnormal pulmonary vasodilatation and/or angiogenesis. • In the present study, we evaluated anti-angiogenesis therapy using...

... developed and occurs during the cholestasis phase. 18 8 2006 1 9 2006 1 9 2006 The Biochemical Society 2007 calcium signalling bile-duct ligation capacitative Ca 2+ entry cholestasis liver cirrhosis sarcoplasmic/endoplasmic-reticulum Ca 2+ -ATPase (SERCA) thrombin...

... creatinine clearance glomerular filtration rate lithium clearance liver cirrhosis sodium excretion 91Clinical Science (2002) 102, 91 98 (Printed in Great Britain) Cimetidine administration and tubular creatinine secretion in patients with compensated cirrhosis Giovanni SANSOEA *, Alberto FERRARI...

...Noemí M. ATUCHA; M. Clara ORTÍZ; Lourdes A. FORTEPIANI; Francisco Javier A. NADAL; Concepción MARTÍNEZ-PRIETO; Joaquín GARCÍA-ESTAÑ The mechanisms that mediate hyporesponsiveness to vasoconstrictors in liver cirrhosis are not completely established. In the present study we have explored the role...

...) in a model of liver cirrhosis induced by chronic bile duct ligation (BDL). Mean arterial pressure (BDL, 111.5±4.7 mmHg; sham-operated, 122.9±3.0 mmHg) and peripheral vascular resistance (BDL, 2.63±0.08 units; sham-operated, 2.93±0.09 units) were lower in BDL rats from day 12 after surgery and decreased...

... with preserved arterial pressure after a bleeding protects cirrhotic rats from ongoing variceal bleeding. 6 5 1997 25 7 1997 © 1997 The Biochemical Society and the Medical Research Society 1997 diazepam ether glomerular filtration rate haemodynamics haemorrhage ketamine liver...

...M. Clara Oriíz; Lourdes A. Fortepiani; Concha Martínez; Noemí M. Atucha; Joaquín García-Estañ 1. The role of nitric oxide as mediator of the vascular alterations present in different models of experimental liver cirrhosis is controversial. In the present study, we evaluated the role of nitric oxide...

... of the fibrosis signal. 29 4 1993 18 5 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 growth factors liver cirrhosis second messenger systems Clinical Science (1993) 85, 281-287 (Printed in Great Britain) 281 Plasma membrane form of phosphatidate...

... patients with liver cirrhosis. The patient group was heterogeneous and varied with respect to the aetiology of cirrhosis, the clinical condition (i.e. Child A or B), the nutritional status and the degree of hyper-insulinaemia. 2. When compared with 10 healthy control subjects the basal plasma adrenaline...

..., showed increased sensitivity to the effects of intravenous diazepam. 5. Psychomotor tests, particularly the Reitan trail test, seem more useful than tests of liver function or drug metabolism for identifying those patients with liver cirrhosis at risk of excessive sedation after diazepam administration...

... syndrome; increased noradrenergic activity is suggested as the likely mechanism. Key words: alcoholism, blood pressure, hyper- tension, liver cirrhosis. Introduction The association of hypertension with alcohol consumption is now well recognized (D Alonzo & Pell, 1968; Klatsky, Friedman, Siegelaub & Gerard...

... words : alcohol, 8-aminolaevulinic acid synthase, anticonvulsants, iron, liver cirrhosis, porphobilinogen, porphyrins, succinyl-CoA. Abbreviations : ALA, 6-aminolaevulinate; CoA, coenzyme A; GSH, reduced glutathione. Introduction Control of hepatic haem synthesis is vested importantly in the fist step...

... 1976 albumin blood pressure blood volume capillary Evans Blue heart failure liver cirrhosis packed cell volume renal artery stenosis renal failure renin Clinical Science and Molecular Medicine (1976) 51, 211s-213s. Significance of increase in labelled albumin disappearance rate...

... Society 1976 anoxaemia chemoreceptors liver cirrhosis liver disease respiration respiratory centre Clinical Science and Molecular Medicine (1976) SO, 25-35. Effect of liver failure on the ventilatory response to hypoxia in man and the goat N. N. STANLEY, S. G. KELSEN AND N. S. CHERNIACK...

... : alkalosis, carbon dioxide, cerebral blood flow, cerebrospinal fluid, cerebral metabolism, liver cirrhosis, ventilatory control. Introduction Hyperventilation, respiratory alkalosis (Vanamee, Poppell, Glicksman, Randall & Roberts, 1956; Tyor & Sieker, 1959; Reinicke, Friis & Mullertz, 1963) and reduced...