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Keywords: liver cirrhosis
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Clin Sci (Lond) (2018) 132 (6): 669–683.
Published: 26 March 2018
...Shao-Jung Hsu; Ming-Hung Tsai; Ching-Chih Chang; Yu-Hsin Hsieh; Hui-Chun Huang; Fa-Yauh Lee; Chiao-Ling Chuang; Ming-Chih Hou; Shou-Dong Lee Liver cirrhosis is characterized by portal hypertension. However, the alteration of portal hypertension-related derangements during cirrhosis resolution...
Clin Sci (Lond) (2017) 131 (1): 69–86.
Published: 09 December 2016
...Hung-Chun Tung; Shao-Jung Hsu; Ming-Hung Tsai; Te-Yueh Lin; I-Fang Hsin; Te-Ia Huo; Fa-Yauh Lee; Hui-Chun Huang; Hsin-Ling Ho; Han-Chieh Lin; Shou-Dong Lee In liver cirrhosis, the altered levels of vasoactive substances, especially endothelin-1 (ET-1) and nitric oxide (NO) lead to elevated...
Clin Sci (Lond) (2015) 129 (6): 449–460.
Published: 22 June 2015
... of anti-inflammation by inhibition of TNF-α/NF-κB/iNOS and anti-angiogenesis by attenuations of VEGF/VEGFR-1,2/Rho-A kinase. hepatopulmonary syndrome inflammatory angiogenesis liver cirrhosis rosuvastatin Focusing on abnormal intrapulmonary inflammations of HPS, we postulated...
Clin Sci (Lond) (2014) 126 (9): 631–632.
Published: 14 January 2014
... Journal compilation © 2014 Biochemical Society 2014 (−)-epigallocatechin-3-gallate (EGCG) angiogenesis green tea polyphenol (GTP) liver cirrhosis portosystemic collateral Cirrhosis, and its main complication PH (portal hypertension), represents a leading cause of mortality worldwide...
Clin Sci (Lond) (2013) 124 (7): 457–466.
Published: 07 December 2012
... with HPS. Using the CBDL-induced HPS animal model, we conducted the present study to evaluate the potentially therapeutic benefit of sorafenib in HPS. Male Sprague–Dawley rats weighing 200–250 g at the time of surgery were used. CBDL-induced liver cirrhosis was used as the HPS experimental model...
Clin Sci (Lond) (2007) 112 (3): 167–174.
Published: 03 January 2007
... developed and occurs during the cholestasis phase. Thus, in order to characterize the molecular basis of the activation of platelets in biliary cirrhosis further, we have studied the mechanisms involved in Ca 2+ signalling in platelets obtained from an experimental model of liver cirrhosis...
Clin Sci (Lond) (2002) 102 (1): 91–98.
Published: 10 December 2001
... creatinine clearance glomerular filtration rate lithium clearance liver cirrhosis sodium excretion 91Clinical Science (2002) 102, 91 98 (Printed in Great Britain) Cimetidine administration and tubular creatinine secretion in patients with compensated cirrhosis Giovanni SANSOEA *, Alberto FERRARI...
Clin Sci (Lond) (2000) 99 (5): 455–460.
Published: 27 October 2000
...Noemí M. ATUCHA; M. Clara ORTÍZ; Lourdes A. FORTEPIANI; Francisco Javier A. NADAL; Concepción MARTÍNEZ-PRIETO; Joaquín GARCÍA-ESTAÑ The mechanisms that mediate hyporesponsiveness to vasoconstrictors in liver cirrhosis are not completely established. In the present study we have explored the role...
Clin Sci (Lond) (2000) 98 (5): 611–617.
Published: 26 April 2000
...) in a model of liver cirrhosis induced by chronic bile duct ligation (BDL). Mean arterial pressure (BDL, 111.5±4.7 mmHg; sham-operated, 122.9±3.0 mmHg) and peripheral vascular resistance (BDL, 2.63±0.08 units; sham-operated, 2.93±0.09 units) were lower in BDL rats from day 12 after surgery and decreased...
Clin Sci (Lond) (1997) 93 (6): 549–556.
Published: 01 December 1997
... with preserved arterial pressure after a bleeding protects cirrhotic rats from ongoing variceal bleeding. 6 5 1997 25 7 1997 © 1997 The Biochemical Society and the Medical Research Society 1997 diazepam ether glomerular filtration rate haemodynamics haemorrhage ketamine liver...
Clin Sci (Lond) (1996) 91 (6): 733–738.
Published: 01 December 1996
...M. Clara Oriíz; Lourdes A. Fortepiani; Concha Martínez; Noemí M. Atucha; Joaquín García-Estañ 1. The role of nitric oxide as mediator of the vascular alterations present in different models of experimental liver cirrhosis is controversial. In the present study, we evaluated the role of nitric oxide...
Clin Sci (Lond) (1993) 85 (3): 281–287.
Published: 01 September 1993
... phosphatidylinositol bisphosphate to DG and inositol trisphosphate [6]. Both the substrate (PA) and the product (DG) of the PAP- Key words: growth factors, liver cirrhosis, second messenger systems. Abbreviations: CBDL, chronic bile duct ligation; DG, diacylglycerol; ECM, extracellular matrix; EGF, epidermal growth...
Clin Sci (Lond) (1982) 63 (1): 75–80.
Published: 01 July 1982
..., showed increased sensitivity to the effects of intravenous diazepam. 5. Psychomotor tests, particularly the Reitan trail test, seem more useful than tests of liver function or drug metabolism for identifying those patients with liver cirrhosis at risk of excessive sedation after diazepam administration...
Clin Sci (Lond) (1979) 57 (s5): 295s–298s.
Published: 01 December 1979
... of alcoholic liver disease. 6. Alcohol-related hypertension may be the result of the alcohol-withdrawal syndrome; increased noradrenergic activity is suggested as the likely mechanism. alcoholism blood pressure hypertension liver cirrhosis © 1979 The Biochemical Society and the Medical Research...
Clin Sci Mol Med (1976) 51 (s3): 211s–213s.
Published: 01 December 1976
... 1976 albumin blood pressure blood volume capillary Evans Blue heart failure liver cirrhosis packed cell volume renal artery stenosis renal failure renin Clinical Science and Molecular Medicine (1976) 51, 211s-213s. Significance of increase in labelled albumin disappearance rate...
Clin Sci Mol Med (1976) 50 (1): 25–35.
Published: 01 January 1976
... Society 1976 anoxaemia chemoreceptors liver cirrhosis liver disease respiration respiratory centre Clinical Science and Molecular Medicine (1976) SO, 25-35. Effect of liver failure on the ventilatory response to hypoxia in man and the goat N. N. STANLEY, S. G. KELSEN AND N. S. CHERNIACK...
Clin Sci Mol Med (1975) 49 (2): 157–169.
Published: 01 August 1975
... : alkalosis, carbon dioxide, cerebral blood flow, cerebrospinal fluid, cerebral metabolism, liver cirrhosis, ventilatory control. Introduction Hyperventilation, respiratory alkalosis (Vanamee, Poppell, Glicksman, Randall & Roberts, 1956; Tyor & Sieker, 1959; Reinicke, Friis & Mullertz, 1963) and reduced...