...Allison B. Reiss; Neal Shah; Dalia Muhieddine; Juan Zhen; Jennifer Yudkevich; Lora J. Kasselman; Joshua DeLeon Dyslipidemia, and specifically elevated low-density lipoprotein (LDL) cholesterol, is one of the most important cardiovascular risk factors. Statins are considered first line therapy...

...Allan D. Sniderman; Jacqueline De Graaf; Patrick Couture; Ken Williams; Robert S. Kiss; Gerald F. Watts The objectives of this analysis are to re-examine the foundational studies of the in vivo metabolism of plasma LDL (low-density lipoprotein) particles in humans and, based on them, to reconstruct...

... in experimental studies. Another potent pro-atherosclerotic risk factor is oxidized low-density lipoprotein (oxLDL). Endothelial cells mediate the uptake of oxLDL by the recently identified lectin-like oxLDL receptor-1 (LOX-1), which accumulates in atherosclerotic lesions. In the present study, we analysed...

..., and there was an apparent rise in serum triacylglycerols from 1.18 to 1.43 mmol/l ( P = 0.15 when adjusted for weight gain). Low-density lipoprotein (LDL)-cholesterol and lipoprotein (a) did not change. In this study, the oxidizability of LDL was unaffected by β-blocker therapy. β-blockade was not associated with any...

... termination of the pacing; samples were used for analyses of lipid profiles, prostacyclin, thromboxane A 2 , lactate and lipid peroxides on plasma and low-density lipoprotein particles. 2. Twenty out of 35 patients who displayed pacing-induced ischaemia were documented by electrocardiographic evidence of ST...

...Juan B. De Sanctis; Isaac Blanca; Nicholas E. Bianco 1. T lymphocytes and large granular lymphocytes internalized chylomicrons, very low-density lipoprotein, low-density lipoprotein, high-density lipoprotein and acetyl modified low-density lipoprotein through different receptors as assessed by flow...

... Society 1992 inflammation low-density lipoprotein lipid peroxidation nuclear magnetic resonance rheumatoid arthritis synovial fluid α-tocopherol Clinical Science (1992) 83, 657-664 (Printed in Great Britain) 651 a -Tocopherol, lipids and lipoproteins in kneejoint synovial fluid and serum...

... in 16 patients with primary glomerular disease, heavy proteinuria, well-preserved renal function and hypercholesterolaemia. 2. Detailed studies of low-density lipoprotein metabolism were performed on eight patients before and after 12 weeks of simvastatin therapy. Radioiodinated tracers were used...

...C. Cortese; P. R. Turner; C. B. Marenah; U. Sule; S. Price; N. E. Miller; B. Lewis 1. Measurements were made of the maximal low-density lipoprotein (LDL) receptor activities of blood lymphocytes from 81 healthy men with a wide range of plasma LDL cholesterol concentrations (1.45-7.55 mmol/l). 2...

...G. Sigurdsson; D. M. Shames; R. J. Havel 1. The mass of the extravascular pool of low-density lipoprotein (LDL) in liver was measured in rats injected intravenously with radioiodinated LDL by determining the radioactive iodine remaining in the extravascular tissues of liver and in plasma when...

...G. R. Thompson; T. Spinks; A. Ranicar; N. B. Myant 1. The non-steady-state turnover of low-density lipoprotein (LDL), labelled in its apoprotein moiety (apo-B) with 131 I, was determined in four patients with familial hypercholesterolaemia, three of them homozygotes. 2. The fractional and absolute...

... a superior exercise performance (assessed by the responses to submaximal test exercise), less body fat, and lower fasting levels for plasma total cholesterol, low-density lipoprotein (LDL) cholesterol, total triglyceride and blood glucose than urban businessmen. Mean plasma HDL cholesterol was considerably...

...G. L. Mills; C. E. Taylaur; M. J. Chapman 1. The low-density lipoproteins (LDL; density 1·007–1·063 g/ml) from two patients homozygous for familial hyperbetalipoproteinaemia have been submitted to chemical and physicochemical analysis. 2. The presence of an anomalous lipoprotein with a low...