... © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 cancer-associated fibroblasts Exosomes JAK2/STAT3 pathway lung cancer miR-210 The authors of the original article “miR- 210 transferred by lung cancer cell-derived exosomes may act...

...Junqiang Fan; Guanxin Xu; Zhibo Chang; Ling Zhu; Jie Yao It has been generally believed that cancer-associated fibroblasts (CAFs) have the ability to increase the process of tumor angiogenesis. However, the potential mechanisms by which cancer-derived exosomes in lung cancer (LC) remains...

... been indicated in tumor metastasis. The melatonin hormone secreted by the pineal gland has an antioxidant effect and protects cells against carcinogenic substances that reduce tumor progression. However, the effects of melatonin in EMT and lung cancer metastasis are largely unknown. We found...

... that induction of autophagy promotes VPRBP–LC3/p62 interaction. Immunohistochemical examination of human NSCLC (non-small cell lung cancer) tissues showed that VPRBP was positively correlated with p62 and negatively correlated with LC3B. Moreover, p62 and VPRBP were associated with poor prognosis in lung ADC...

... as a lineage-specific proto-oncogene for lung cancer. Correspondence: Dr Vijay Boggaram (email [email protected] ). 29 2 2008 1 5 2008 19 5 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 TTF-1 [thyroid transcription factor-1; also known...

...Robert C. RINTOUL; Tariq SETHI Tumour recurrence following chemotherapy remains a major obstacle to the cure of many cancers. This is exemplified by small-cell lung cancer (SCLC). Host-tumour interactions are central to tumour survival and proliferation. We hypothesized that a factor(s) within...

...R. Thomas JAGOE; Christopher P.F. REDFERN; Russell G. ROBERTS; G. John GIBSON; Timothy H.J. GOODSHIP Muscle wasting is a common and prominent feature of advanced cancer, including lung cancer. Evidence from animal experiments suggests that accelerated proteolysis via the ubiquitin-proteasome...

... in patients with advanced lung cancer. The present study was aimed at exploring the effects of ATP on whole-body glucose turnover, alanine turnover and gluconeogenesis from alanine. Twelve patients with advanced non-small-cell lung cancer (NSCLC) were studied 1 week before and during 22–24 h of continuous ATP...

...Susanne LEIJ-HALFWERK; Pieter C. DAGNELIE; J. Willem O. VAN DEN BERG; J. H. Paul WILSON; Paul E. SIJENS Stable-isotope tracers were used to assess whether levels of phosphomonoesters (PME) and phosphodiesters (PDE) in the livers of lung cancer patients, as observed by 31 P magnetic resonance (MR...