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Mark R. Edwards, Pervez Sultan, Ana Gutierrez del Arroyo, John Whittle, Shamir N. Karmali, S. Ramani Moonesinghe, Fares S. Haddad, Michael G. Mythen, Mervyn Singer, Gareth L. Ackland
Clin Sci (Lond) (2015) 129 (5): 423–437.
Published: 11 June 2015
... confirmed prospectively that preoperative lymphopenia (≤1.3 x 10 9 ·l −1 ; <20% white cell count; prevalence 15–18%) was associated with infectious complications (relative risk 1.5 (95% confidence interval 1.1–2.0); P =0.008) and prolonged hospital stay. Lymphocyte respirometry, mitochondrial...
Includes: Supplementary data
Yun Lin, Amanda Damjanovic, E. Jeffrey Metter, Huy Nguyen, Thai Truong, Kevin Najarro, Christa Morris, Dan L. Longo, Ming Zhan, Luigi Ferrucci, Richard J. Hodes, Nan-ping Weng
Clin Sci (Lond) (2015) 128 (6): 367–377.
Published: 28 November 2014
... report a longitudinal analysis of telomere length in the PBMCs, lymphocytes and monocytes of 216 human subjects aged from 20–90 years assessed at 0-, 5- and 12-year follow-up. For the 5- and 12-year follow-up, telomere length in the PBMCs decreased in 34% and 46%, exhibited no detectable change in 56...
Includes: Supplementary data
Germán E. González, Nour-Eddine Rhaleb, Pablo Nakagawa, Tang-Dong Liao, Yunhe Liu, Pablo Leung, Xiangguo Dai, Xiao-Ping Yang, Oscar A. Carretero
Clin Sci (Lond) (2014) 126 (1): 85–94.
Published: 09 September 2013
...). However, it is not known whether Ac-SDKP decreases collagen cross-linking and lymphocyte infiltration; lymphocytes modulate both collagen cross-linking and ECM (extracellular matrix) formation in hypertension. Thus we hypothesized that (i) in AngII (angiotensin II)-induced hypertension, Ac-SDKP prevents...
Clin Sci (Lond) (2007) 112 (1): 59–67.
Published: 01 December 2006
...Juliana Pires; Rui Curi; Rosemari Otton The aim of the present study was to investigate whether fasting for 24 and 48 h induces apoptosis of rat mesenteric lymph node lymphocytes similar to that observed previously in diabetic patients and alloxan-induced diabetic rats. Several features...
Clin Sci (Lond) (2006) 110 (3): 379–386.
Published: 10 February 2006
... of infiltrating killer lymphocytes. Olmesartan also decreased the expression of CVB3 genomes in myocardial tissue as well as serum levels of 8-OHdG (8-hydroxy-2′-deoxyguanosine), a biomarker of oxidative-stress-induced DNA damage. The findings suggest that olmesartan prevents myocardial damage and may improve...
Clin Sci (Lond) (2005) 108 (3): 245–253.
Published: 18 February 2005
... by Jurkat (a human T-lymphocyte-derived cell line) and Raji (a human B-lymphocyte-derived cell line) cells were investigated. ROS production was determined by NBT (Nitro Blue Tetrazolium) reduction (intracellular and extracellular ROS production) and by dihydroethidium oxidation using flow cytometry...
Clin Sci (Lond) (1990) 79 (5): 531–536.
Published: 01 November 1990
...Pasquale Strazzullo; Mitzy Canessa 1. A human lymphocyte preparation, obtained by Percoll gradient centrifugation and free of contaminating monocytes and granulocytes, was used to study the kinetics of the Na + -H + exchanger through activation by nigericin-induced acidic loading. The fluorescent...
Clin Sci (Lond) (1990) 78 (2): 199–206.
Published: 01 February 1990
...) 86 Rb + influx and sodium-potassium-pump-independent (ouabain-resistant) 86 Rb + influx in lymphocytes in vitro . 2. The subjects comprised euthyroid and thyrotoxic men with hypokalaemic periodic paralysis between attacks, men with uncomplicated thyrotoxicosis, and healthy men matched for age...
K. Pritchard, A. E. G. Raine, C. C. Ashley, L. M. Castell, V. Somers, C. Osborn, J. G. G. Ledingham, J. Conway
Clin Sci (Lond) (1989) 76 (6): 631–635.
Published: 01 June 1989
...K. Pritchard; A. E. G. Raine; C. C. Ashley; L. M. Castell; V. Somers; C. Osborn; J. G. G. Ledingham; J. Conway 1. Fifty-two normotensive and essential hypertensive subjects were studied. Intracellular free calcium concentration ([Ca 2+ ] i ) was measured in lymphocytes (37 subjects) and platelets...
Clin Sci (Lond) (1988) 74 (3): 331–334.
Published: 01 March 1988
... to acute stress may provide additional insights into the age effect on these responses. 2. We measured supine and 10 min upright plasma noradrenaline and lymphocyte adenylate cyclase activity in ten healthy elderly subjects (age 66–80 years) and seven healthy young subjects (age 27–34 years). 3...
Clin Sci (Lond) (1987) 73 (6): 605–611.
Published: 01 December 1987
...K. Pattanapanyasat; T. G. Hoy; A. Jacobs 1. Measurements of T-lymphocyte surface ferritin using flow cytometry show that phytohaemagglutinin (PHA) stimulation causes a marked increase in the number of cells bearing spleen-type (S) and heart-type (H) ferritin on their membrane, whereas...
Clin Sci (Lond) (1984) 67 (4): 407–411.
Published: 01 October 1984
...A. Montanari; Isabella Simoni; E. Sani; P. Schianchi; A. Borghetti; A. Novarini 1. Peripheral blood lymphocytes were isolated at room temperature in a low sodium medium in 17 normotensive control subjects (NC) and 13 patients with essential hypertension (EHP). 2. Lymphocyte sodium content...
Clin Sci Mol Med (1974) 47 (4): 399–402.
Published: 01 October 1974
...A. Venetianer; L. Dallmann; A. László; K. Burg 1. A new technique has been developed for the detection of inborn errors of mucopolysaccharide metabolism by measurement of the incorporation of radioactive sulphate into lymphocytes stimulated by phytohaemagglutinin. 2. Incorporation of 35 SO 4...