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Keywords: magnesium
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Clin Sci (Lond) (2015) 129 (12): 1143–1150.
Published: 30 October 2015
...Martin Kolisek; Augusto C. Montezano; Gerhard Sponder; Aikaterini Anagnostopoulou; Juergen Vormann; Rhian M. Touyz; Joerg R. Aschenbach Disturbed magnesium (Mg 2+ ) homoeostasis and increased levels of OS (oxidative stress) are associated with poor clinical outcomes in patients suffering from...
Clin Sci (Lond) (2012) 123 (1): 1–14.
Published: 12 March 2012
...Anke L. Lameris; Leo A. Monnens; René J. Bindels; Joost G. J. Hoenderop Magnesium (Mg 2+ ) balance is tightly regulated by the concerted actions of the intestine, bone and kidneys. This balance can be disturbed by a broad variety of drugs. Diuretics, modulators of the EGFR (epidermal growth factor...
Clin Sci (Lond) (2012) 122 (9): 397–407.
Published: 21 December 2011
...Jeanette A. M. Maier There is no doubt that the functional and structural integrity of the endothelium is critical in maintaining vascular homoeostasis and in preventing atherosclerosis. In the light of epidemiological and experimental studies, magnesium deficiency is emerging as an inducer...
Clin Sci (Lond) (2004) 106 (3): 269–277.
Published: 01 March 2004
...Lionel DUMONT; Christopher LYSAKOWSKI; Martin R. TRAMÈR; Jean-Daniel JUNOD; Chahé MARDIROSOFF; Edömer TASSONYI; Bengt KAYSER Magnesium is a physiological N -methyl- D -aspartate (NMDA) antagonist. The NMDA receptor may be involved in the pathogenesis of acute mountain sickness (AMS). In the present...
Clin Sci (Lond) (2004) 106 (3): 279–285.
Published: 01 March 2004
... flow velocity in the middle cerebral artery (MCAv) may be used as a proxy measure of cerebral blood flow. Using transcranial Doppler sonography, MCAv was measured during normo- and hyper-ventilation in subjects who participated in a trial that tested the effect of magnesium supplementation...
Clin Sci (Lond) (2000) 99 (4): 285–292.
Published: 31 August 2000
... there are modifications in the renal tubular handling of magnesium and other electrolytes, or in the tissue deposition of magnesium, which may account for the hypomagnesaemia. We have also investigated whether parathyroid hormone has a role in the observed hypomagnesaemia. Two studies have been performed; in the first we...
Clin Sci (Lond) (2000) 98 (4): 375–380.
Published: 24 February 2000
... normoxic conditions were not significantly higher than those in non-incubated tissue. The DNA laddering activity of placental explants after 2 h of incubation under hypoxic conditions was significantly increased with increased concentrations of magnesium, but remained unchanged by the inclusion...
Clin Sci (Lond) (2000) 98 (2): 175–181.
Published: 11 January 2000
...Shota SASAKI; Tetsuya OSHIMA; Hideo MATSUURA; Ryoji OZONO; Yukihito HIGASHI; Nobuo SASAKI; Toshiyuki MATSUMOTO; Yukiko NAKANO; Atsushi UEDA; Atsunori YOSHIMIZU; Satoshi KURISU; Masayuki KAMBE; Goro KAJIYAMA To investigate magnesium status in patients with cardiovascular diseases and in those...
Clin Sci (Lond) (1998) 95 (5): 583–587.
Published: 01 November 1998
...Klaus KISTERS; Ernst-Rudolf KREFTING; Claus SPIEKER; Walter ZIDEK; Karl Heinz DIETL; Michael BARENBROCK; Karl Heinz RAHN 1. Although in blood cells decreased magnesium concentrations and increased sodium concentrations in essential hypertension have often been described, only sparse data exist...
Clin Sci (Lond) (1998) 95 (2): 137–142.
Published: 01 August 1998
...Ligia J. DOMINGUEZ; Mario BARBAGALLO; Gabriele Di LORENZO; Agata DRAGO; Santi SCOLA; Giuseppina MORICI; Calogero CARUSO 1. Increased bronchial smooth muscle contractility with consequent bronchial hyperreactivity are characteristic physiopathological events of asthma. Since magnesium intervenes...
Clin Sci (Lond) (1996) 91 (3): 347–351.
Published: 01 September 1996
...Gaudenz Hafen; Regula Laux-End; Anita C. Truttmann; Andreas Schibler; John A. S. McGuigan; Edgar Peheim; Mario G. Bianchetti 1. Respiratory alkalosis accompanies the clinical syndrome of tetany, precipitates cardiac arrhythmias and predisposes to coronary vasoconstriction. Magnesium plays...
Clin Sci (Lond) (1992) 83 (5): 561–565.
Published: 01 November 1992
...Mario Barbagallo; Lawrence M. Resnick; R. Ernest Sosa; Mary Lou Corbett; John H. Laragh 1. To determine whether abnormal renal calcium excretion is unique to primary genetic hypertension, blood pressure and 24 h urinary excretion of calcium, magnesium, sodium and creatinine were measured...
Clin Sci (Lond) (1991) 81 (3): 297–304.
Published: 01 September 1991
... on admission (0.59 ± 0.23 mmol/l) correlated significantly with the simultaneous renal threshold phosphate concentration (0.68 ± 0.33 mmol/l; r = 0.607, P < 0.025) and both parameters rose in parallel during treatment. 4. Plasma magnesium concentrations were normal (0.75–1.05 mmol/l) in 108 patients (62.8...
Clin Sci (Lond) (1991) 80 (6): 539–547.
Published: 01 June 1991
... lectins lymphocytes magnesium Clinical Science (1991) 80,539-547 539 Intracellular free magnesium in human lymphocytes and the response to lectins L. L. NG', J. E. DAVIES2 AND M. C. GARRIDO* 'Department of Pharmacology, Leicester Royal Infirmary, Leicester, U.K., and 2Sheikh Rashid Diabetes Unit...
Clin Sci (Lond) (1990) 79 (5): 499–504.
Published: 01 November 1990
... of provoking more complex and sustained arrhythmias. 4. The effect of pressure changes were highly dependent upon electrolyte concentrations in the perfusate. Low potassium and magnesium concentrations increased the amount of arrhythmia provoked by pressure increases but tended to reduce that provoked...
Clin Sci (Lond) (1990) 78 (3): 255–259.
Published: 01 March 1990
...B. J. Lipworth; D. G. McDevitt; A. D. Struthers 1. Twelve normal subjects were given 5 days' treatment with (a) placebo; (b) 5 mg of bendrofluazide; (c) 5 mg of bendrofluazide plus 24 mmol of potassium; (d) 5 mg of bendrofluazide plus 24 mmol of magnesium; (e) 5 mg of bendrofluazide plus 24 mmol...
Clin Sci (Lond) (1990) 78 (2): 185–191.
Published: 01 February 1990
...L. A. Corr; R. M. Grounds; J. L. Beacham; J. G. Whitwam; M. J. Brown 1. To examine the metabolic effects of increases in circulating endogenous plasma catecholamines, we measured plasma glucose, potassium and magnesium in 14 patients undergoing elective coronary artery bypass grafting. The patients...
Clin Sci (Lond) (1988) 75 (6): 661–667.
Published: 01 December 1988
...R. Mathew; E. S. Gloster; B. T. Altura; B. M. Altura 1. The effect of oral magnesium aspartate hydrochloride on monocrotaline (MCT)-induced pulmonary arterial hypertension was evaluated in rats. 2. A single subcutaneous injection of MCT, a pyrrolizidine alkaloid of plant origin, induces significant...
Clin Sci (Lond) (1988) 75 (5): 509–514.
Published: 01 November 1988
... of cyclosporin/kg daily. 2. After 7 days of cyclosporin treatment, plasma magnesium concentration was 1.04 ±0.01 mmol/l in control rats compared with 0.85 ±0.01 mmol/l in group II and 0.81 ±0.02 mmol/l in group III. After 14 days of cyclosporin administration, group III rats developed severe hypomagnesaemia...
Clin Sci (Lond) (1988) 75 (5): 543–549.
Published: 01 November 1988
... and magnesium increased, whereas the free fatty acids and glycerol concentrations in serum were reduced. These two changes presumably balanced each other, as the plasma ionized calcium and serum parathyroid hormone concentrations were not significantly altered. 6. There were no consistent relationships between...
Clin Sci (Lond) (1988) 75 (4): 395–402.
Published: 01 October 1988
...D. M. Tillman; P. F. Semple 1. Because disturbances of calcium metabolism have been described in hypertension, measurements of plasma and serum concentrations of ionized calcium, total calcium, magnesium and renin were made in 38 patients with essential hypertension and age- and sex-matched control...
Clin Sci (Lond) (1988) 74 (6): 595–597.
Published: 01 June 1988
...W. J. W. Bos; D. S. Postma; J. J. van Doormaal 1. The effect of terbutaline infusion over 4 h on serum levels of potassium, ionized calcium, phosphate and magnesium and urinary excretion of potassium, calcium, magnesium and adenosine 3′:5′-cyclic monophosphate was studied in six healthy volunteers...
Clin Sci (Lond) (1988) 74 (5): 513–517.
Published: 01 May 1988
...K. L. Woods; D. Walmsley; A. M. Heagerty; D. L. Turner; Lu-Yun Lian 1. 31 P n.m.r. spectroscopy was used to measure the dissociation constant of MgATP under simulated intracellular conditions and to measure erythrocyte free magnesium concentration. 2. In a group of 40 subjects, the relationship...
Clin Sci (Lond) (1988) 74 (3): 241–248.
Published: 01 March 1988
... and the Medical Research Society 1970 magnesium muscle biopsies potassium sodium sodium potassium pumps Clinical Science ( 1988) 74,24 1-248 24 1 A simple and rapid method for the determination of the concentrations of magnesium, sodium, potassium and sodium, potassium pumps in human skeletal muscle...
Clin Sci (Lond) (1987) 73 (4): 411–416.
Published: 01 October 1987
... amount after alcohol and the isocaloric glucose control drink, but peak plasma insulin levels were higher after the control drink. 5. Plasma sodium rose in keeping with alcohol induced water diuresis. No significant changes in plasma potassium or magnesium were seen after alcohol. 6. Compared...
Clin Sci (Lond) (1987) 72 (1): 135–138.
Published: 01 January 1987
...Kenneth F. Whyte; George J. Addis; Robert Whitesmith; John L. Reid 1. Regulation of magnesium balance is poorly understood. However, hypomagnesaemia has been reported in patients in clinical situations where circulating catecholamines are raised including myocardial infarction, cardiac surgery...
Clin Sci (Lond) (1986) 71 (6): 703–712.
Published: 01 December 1986
... subjects. 2. Muscle samples were analysed to obtain intracellular bicarbonate and pH values from total acid-labile carbon dioxide content. Muscle potassium, magnesium and sodium content were also determined, as well as water compartments. 3. Skeletal muscle of COLD patients with ARF showed intracellular...
Clin Sci (Lond) (1986) 70 (3): 277–284.
Published: 01 March 1986
...Norman L. M. Wong; Gary A. Quamme; John H. Dirks 1. Clearance and micropuncture studies were performed in four groups of acutely thyropara-thyroidectomized animals to study the effects of alkalosis and acidosis on the renal handling of magnesium. 2. Our results indicate that chronic metabolic...
Clin Sci (Lond) (1984) 66 (4): 465–471.
Published: 01 April 1984
...I. W. Booth; P. J. Milla; J. T. Harries 1. The effects of MgCl 2 on the electrical characteristics and sodium and chloride transport in short-circuited rabbit terminal ileum in vitro were studied. 2. Increasing the magnesium concentration from a basal concentration of 1.1 mmol/l to either 2.5...
Clin Sci (Lond) (1982) 62 (1): 17–19.
Published: 01 January 1982
...P. C. Hallson; G. A. Rose; S. Sulaiman 1. A low urinary magnesium was induced in normal volunteer subjects by giving cellulose phosphate; magnesium was added in vitro to yield urine samples of normal and high magnesium concentrations 2. After rapid evaporation of these urine samples at pH 5.3...
Clin Sci (Lond) (1980) 58 (3): 255–257.
Published: 01 March 1980
...R. Lindsay; D. M. Hart; C. Forrest 1. Serum, urinary and erythrocyte magnesium concentrations were measured in groups of premenopausal, postmenopausal and oophorectomized women. 2. Serum and urinary magnesium were both significantly higher in postmenopausal and oophorectomized women than...
Clin Sci Mol Med (1976) 51 (6): 589–599.
Published: 01 December 1976
... loss of intracellular potassium and an increase in intracellular sodium concentration. The muscle magnesium content was also slightly decreased. After repletion with potassium chloride, muscle sodium and potassium became normal. 4. The contents of creatine phosphate, ATP, ADP, AMP, lactate and pyruvate...
Clin Sci Mol Med (1976) 51 (2): 161–168.
Published: 01 August 1976
...A. M. Parfitt 1. Previously published data obtained by magnesium infusion in man were found to conform to a T m /glomerular filtration rate (GFR) model on the assumption of 80% diffusibility of plasma magnesium. The lower limit of T m,Mg /GFR was 625 μmol/l. 2. Previously published data concerning...
Clin Sci Mol Med (1976) 50 (2): 91–102.
Published: 01 February 1976
... results. 3. The lower dose of angiotensin inhibited distal sodium, chloride, water and magnesium reabsorption, inhibited distal hydrogen secretion and stimulated distal potassium secretion. The higher dose of angiotensin produced these changes and additionally inhibited distal calcium reabsorption. Most...
Clin Sci Mol Med (1975) 49 (2): 83–90.
Published: 01 August 1975
..., there was a prompt and sustained fall in urinary calcium with no change in plasma calcium, indicating increased tubular reabsorption. Plasma and urinary magnesium fell, without increase in tubular reabsorption. The urinary total hydroxyproline increased and T m,P / glomerular filtration rate fell after 2 days...
Clin Sci Mol Med (1974) 46 (3): 357–367.
Published: 01 March 1974
...A. Hodgkinson 1. The daily excretion of oxalate, calcium, magnesium and creatinine was determined in fifty-two normal men and sixty-five male patients with calcium oxalate-containing renal stones. 2. Direct relationships were found between calcium and oxalate excretion, magnesium and oxalate...
Clin Sci Mol Med (1973) 45 (6): 751–764.
Published: 01 December 1973
...S. P. Gray; J. E. W. Morris; C. J. Brooks 1. Fifteen healthy young men were exposed to an atmosphere of 0–7% CO 2 in air for 7 weeks. 2. For 1 week before and during the exposure to CO 2 , serum calcium, magnesium and inorganic phosphate (P i ) levels were measured at intervals, together with 24 h...