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Keywords: matrine
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Xuhua Yu, Huei Jiunn Seow, Hao Wang, Desiree Anthony, Steven Bozinovski, Lin Lin, Ji-Ming Ye, Ross Vlahos
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (4): 551–564.
Published: 18 February 2019
... that initiates and drives the long-term progression of disease. In particular, there are no effective therapeutics that target neutrophilic inflammation in COPD, which is known to cause tissue damage by degranulation of a suite of proteolytic enzymes including neutrophil elastase (NE). Matrine, an alkaloid...