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Keywords: mechanotransduction
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Clin Sci (Lond) (2021) 135 (10): 1209–1212.
Published: 20 May 2021
... present commentary, we discuss the potential implications for other, more common non-atherosclerotic microvascular diseases: INOCA and HFpEF. The relation to mechanotransduction, to cellular senescence and to sGC activators as potential intervention agents are described. Correspondence: Anton J.M...
Clin Sci (Lond) (2021) 135 (9): 1189–1207.
Published: 14 May 2021
... the contractile response. Focal adhesions (FAs) are conceivable candidates that may influence SMC contraction. They are required for actin-based traction employed by cells to sense and respond to environmental cues in a process termed mechanotransduction. Depletion of FA proteins impairs SMC...
Clin Sci (Lond) (2020) 134 (17): 2399–2418.
Published: 16 September 2020
... cues to initiate intracellular signaling pathway(s), thereby changing cellular behaviors and functions. However, the precise role of matrix–cell interactions involved in mechanotransduction during vascular homeostasis and disease development remains to be fully determined. In this review, we introduce...
Clin Sci (Lond) (2020) 134 (11): 1245–1253.
Published: 05 June 2020
... 03 2020 15 05 2020 22 05 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 biophysics mechanotransduction podocytes Conventional thinking in cell biology often assumes that cells communicate mostly via biochemical...