...Michael H. Chiu; Bobak Heydari; Zarah Batulan; Nadia Maarouf; Vinita Subramanya; Karin Schenck-Gustafsson; Edward R. O’Brien The recognition of sex differences in cardiovascular disease, particularly the manifestations of coronary artery disease (CAD) in post-menopausal women, has introduced new...

... on the expression and function of GPER in hypertension, kidney disease, atherosclerosis, vascular remodelling, heart failure, reproduction, metabolic disorders, cancer, environmental health and menopause. Furthermore, this review will highlight the potential of GPER as a therapeutic target. In 1997, a cDNA screen...

...Rodrigo Maranon; Jane F. Reckelhoff In recent years, the interest in studying the impact of sex steroids and gender on the regulation of blood pressure and cardiovascular disease has been growing. Women are protected from most cardiovascular events compared with men until after menopause...

... controls by time since menopause and by body mass index. Serum levels of androstenedione and total testosterone were measured by radioimmunoassays. Free testosterone was calculated from total testosterone, immunoassayed sex hormone-binding globulin and albumin. The mean±S.D. serum level of androstenedione...

... of the adductor pollicis muscle in 273 subjects aged 17–90 years (176 men, 30 premenopausal women and 67 peri- or post-menopausal women who were not receiving hormone replacement therapy). 2. To determine whether the loss of specific muscle force is hormone-dependent in women, we studied a further 25 women, aged...

... challenge samples. 2. Using a multivariate regression model, with predictor variables of chronological age, menopausal age and body mass index, neither chronological age nor menopausal age correlated with fasting or post-challenge plasma glucose or C-peptide concentrations. In contrast, menopausal age...

...Peter L. Selby; Munro Peacock; Stuart A. Barkworth; Wendy B. Brown; Geoffrey A. Taylor 1. The early effects of sex steroid therapy were assessed in 28 normal post-menopausal women, 18 treated with ethinyloestradiol and 10 with norethisterone. 2. There was a reduction in the fasting urinary...

...-menopausal women with various degrees of simple osteoporosis, but a few cases of hyperparathyroidism and other calcium disorders were included. 2. Calcium balance, bone resorption rate, urinary hydroxyproline and plasma alkaline phosphatase were shown to be related to the rate of bone loss; patients...

.... It is proposed that the rise in the plasma alkaline phosphatase, like that in the hydroxyproline excretion, may reflect the onset of bone loss that occurs after the menopause. © 1980 The Biochemical Society and the Medical Research Society 1980 28 9 1979 2 1 1980 hydroxyproline menopause...

... Society and the Medical Research Society 1980 erythrocyte magnesium menopause oestrogen Clinical Science (1980) 58,255-257 SHORT COMMUNICATION Effect of a natural and artificial menopause on serum, urinary and erythrocyte magnesium R. LINDSAY, D. M. H A R T AND C. F O R R E S T Weslern...

.... It is concluded that oophorectomy and calcium deficiency each reduce bone mass in the adult rat but the greatest effect is seen when they are combined. 25 7 1977 22 11 1977 © 1978 The Biochemical Society and the Medical Research Society 1978 bone diseases calcium dietary menopause...

...B. Pelc; D. H. Marshall; P. Guha; M. Y. Khan; B. E. C. Nordin 1. Plasma androstenedione, plasma oestrone and the conversion of plasma androstenedione into oestrone were measured in 19 post-menopausal women without fractures (six of them oophorectomized) and 18 with vertebral or femoral neck...