1-13 of 13
Keywords: metformin
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Articles
Articles
Articles
Clin Sci (Lond) (2017) 131 (1): 27–36.
Published: 09 December 2016
...François Cauchy; Mouniya Mebarki; Benjamin Leporq; Samira Laouirem; Miguel Albuquerque; Simon Lambert; Pierre Bourgoin; Olivier Soubrane; Bernard E. Van Beers; Sandrine Faivre; Pierre Bedossa; Valérie Paradis Studies suggest that metformin, widely used for treating Type 2 diabetes, possesses innate...
Includes: Supplementary data
Articles
Articles
Clin Sci (Lond) (2012) 122 (12): 555–573.
Published: 05 March 2012
... pathways that can activate AMPK using isogenic cell lines stably expressing either wild-type AMPK complexes or AMP-insensitive (R531G) γ2 mutants. AMP-activated protein kinase (AMPK) autophagy cardiovascular disease energy sensor metformin stress All living organisms face the challenge...
Articles
Clin Sci (Lond) (2012) 122 (6): 253–270.
Published: 11 November 2011
...Benoit Viollet; Bruno Guigas; Nieves Sanz Garcia; Jocelyne Leclerc; Marc Foretz; Fabrizio Andreelli Considerable efforts have been made since the 1950s to better understand the cellular and molecular mechanisms of action of metformin, a potent antihyperglycaemic agent now recommended as the first...
Articles
Articles
Articles
Articles
Clin Sci (Lond) (2009) 116 (8): 607–620.
Published: 16 March 2009
...; consequently, they have been implicated in cardiac ischaemia, arrhythmias and hypertrophy. Recent mechanistic studies have shown that AMPK has an important role in the mechanism of action of MF (metformin), TDZs (thiazolinediones) and statins. Increased understanding of the beneficial effects of AMPK...
Articles
Articles
Clin Sci (Lond) (1987) 73 (1): 41–45.
Published: 01 July 1987
...P. Leslie; R. T. Jung; T. E. Isles; J. Baty 1. In the management of the non-insulin dependent diabetic patient, metformin often facilitates weight loss whereas sulphonylurea may predispose to weight gain. To investigate whether this is due to alterations in energy expenditure we have studied energy...