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1-7 of 7
Keywords: methylglyoxal
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (8): 697–706.
Published: 26 April 2023
...Xiaodi Zhang; Jean L.J.M. Scheijen; Coen D.A. Stehouwer; Kristiaan Wouters; Casper G. Schalkwijk The dicarbonyl compound methylglyoxal (MGO) is a major precursor in the formation of advanced glycation endproducts (AGEs). MGO and AGEs are increased in subjects with diabetes and are associated...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (11): 819–824.
Published: 30 May 2022
...Naila Rabbani The study of the glyoxalase system by Thornalley and co-workers in clinical diabetes mellitus and correlation with diabetic complications revealed increased exposure of patients with diabetes to the reactive, dicarbonyl metabolite methylglyoxal (MG). Twenty-eight years later, extended...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (19): 1677–1696.
Published: 23 August 2016
... metabolism of dicarbonyl metabolites. MG (methylglyoxal) is a dicarbonyl metabolite of relatively high flux of formation and precursor of the most quantitatively and functionally important spontaneous modifications of protein and DNA clinically. Major MG-derived adducts are arginine-derived hydroimidazolones...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2015) 128 (12): 839–861.
Published: 27 March 2015
...Dionne E.M. Maessen; Coen D.A. Stehouwer; Casper G. Schalkwijk The formation and accumulation of advanced glycation endproducts (AGEs) are related to diabetes and other age-related diseases. Methylglyoxal (MGO), a highly reactive dicarbonyl compound, is the major precursor in the formation of AGEs...
Articles
Jorge BERLANGA, Danay CIBRIAN, Isabel GUILLÉN, Freya FREYRE, José S. ALBA, Pedro LOPEZ-SAURA, Nelson MERINO, Alfredo ALDAMA, Ana M. QUINTELA, Maria E. TRIANA, Jose F. MONTEQUIN, Hussam AJAMIEH, Dioslaida URQUIZA, Naila AHMED, Paul J. THORNALLEY
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (1): 83–95.
Published: 23 June 2005
...Jorge BERLANGA; Danay CIBRIAN; Isabel GUILLÉN; Freya FREYRE; José S. ALBA; Pedro LOPEZ-SAURA; Nelson MERINO; Alfredo ALDAMA; Ana M. QUINTELA; Maria E. TRIANA; Jose F. MONTEQUIN; Hussam AJAMIEH; Dioslaida URQUIZA; Naila AHMED; Paul J. THORNALLEY Increased formation of MG (methylglyoxal) and related...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (5): 575–582.
Published: 01 November 1996
... correlated positively with haemoglobin A 1c in diabetic patients. In insulin-dependent patients, the concentration of methylglyoxal was also in the logistic model for retinopathy and diabetic complications, but the logistic regression coefficient was not significant. 3. Multiple linear regression analysis...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1994) 87 (1): 21–29.
Published: 01 July 1994
...Antony C. McLellan; Paul J. Thornalley; Jonathan Benn; Peter H. Sonksen 1. The metabolism of methylglyoxal by the glyoxalase system may be linked to the development of diabetic complications. The glyoxalase system was characterized in blood samples from patients with insulin-dependent diabetes...