...David P. Brooks; Gerald R. Rhodes; Paul Woodward; Venkata K. Boppana; Francine M. Mallon; H. Eugene Griffin; Lewis B. Kinter 1. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure 2. We measured methylguanidine in the plasma of dogs with acute ischaemic-induced renal...

...M. Gonella; G. Barsotti; S. Lupetti; S. Giovannetti 1. Methylguanidine administered orally to normal volunteers was almost completely recovered in the urine, indicating that it is absorbed in the gastrointestinal tract and is not converted into other compounds. In normal persons at least, its...

...P. L. Balestri; P. Rindi; M. Biagini; S. Giovannetti 1. Uptake of glucose by the rat diaphragm in vitro and utilization of glucose by human erythrocytes were inhibited by urea, creatinine and, to an even greater extent, by urea plus creatinine. Guanidine, methylguanidine and guanidinoacetic acid...