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Keywords: microRNA (miRNA)
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Clin Sci (Lond) (2017) 131 (5): 411–423.
Published: 17 February 2017
... at a concentration of 10 μM. © 2017 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2017 diabetic nephropathy kidney fibrosis mesangial cells microRNA (miRNA) transforming growth factor-β (TGF-β1) Gene expression was analysed by qPCR, performed...
Includes: Supplementary data
Clin Sci (Lond) (2017) 131 (3): 181–195.
Published: 05 January 2017
...-based therapies and the in vitro models to study CAVD are inadequate or lacking. Here, we present a forward-looking review of 3D CAVD models, miRNA-based therapeutics and controlled drug-delivery strategies. aortic valve calcification 3D model drug delivery microRNA (miRNA...
Clin Sci (Lond) (2015) 128 (3): 153–180.
Published: 03 October 2014
...Monica Logan; Shannon M. Hawkins microRNAs (miRNAs) are small RNA molecules that represent the top of the pyramid of many tumorigenesis cascade pathways as they have the ability to affect multiple, intricate, and still undiscovered downstream targets. Understanding how miRNA molecules serve...
Clin Sci (Lond) (2014) 126 (3): 183–194.
Published: 01 October 2013
...) [ 1 , 8 , 9 ]. cardiovascular disease diabetes dyslipidaemia hypertension microRNA (miRNA) The biogenesis of miRNAs starts with RNA polymerase II-mediated transcription from the genome, leading to the formation of a pri-miRNA (primary miRNA transcript) of variable length depending...
Clin Sci (Lond) (2014) 126 (2): 95–110.
Published: 13 September 2013
..., a novel class of non-coding RNA, microRNA (miRNA), have emerged as being important regulators of numerous biological functions. Among these functions are basic maintenance of cell signalling and tissue architecture. Disruption of miRNA levels can contribute not only to the development of the chronic...
Clin Sci (Lond) (2012) 122 (10): 439–447.
Published: 20 January 2012
... (email mliang@mcw.edu ). 25 3 2011 11 10 2011 1 11 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 diagnosis hypertension kidney microRNA (miRNA) therapy translational research An easy way for clinicians to get an initial understanding...
Clin Sci (Lond) (2010) 119 (9): 395–405.
Published: 23 July 2010
... The Authors Journal compilation © 2010 Biochemical Society 2010 angiotensin-converting enzyme inhibitor (ACEI) angiotensin II receptor blocker (ARB) atherosclerosis interleukin-1-receptor-associated kinase 1 (IRAK1) microRNA (miRNA) Toll-like receptor 4 (TLR4) tumour-necrosis-factor-receptor...
Clin Sci (Lond) (2010) 119 (8): 335–343.
Published: 06 July 2010
... of the Creative Commons Attribution Non-Commercial Licence ( http://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. coronary artery disease (CAD) gene expression microRNA...
Includes: Supplementary data