... vesicle microparticles placenta pregnancy The lungs and the liver are the major sites in which placental large-EVs were detected. Following tail vein administration into non-pregnant and pregnant mice, human placental large-EVs are seen exclusively in the lungs at 2 min, with gradually...

... agreement with Portland Press and the Biochemical Society under a transformative agreement with CAUL. glucose homeostasis insulin resistance microparticles pancreatic beta cell Gestational diabetes mellitus (GDM) is defined as glucose intolerance with onset during pregnancy [ 1...

..., leading to endothelial dysfunction. In the present study, we investigated the associations between habitual sodium intake and RAAS blockade on endothelial function by measuring circulating microparticles (MPs) in individuals with T2D. Methods: We conducted a prospective, cross-sectional study in 74...

... cycles/h) stimulated the ER stress response and microparticle(s) (MP) production from both SMC and endothelial cell(s) (EC) in a time-dependent manner. Treatment of EC with isolated MP led to anoikis, which was determined by measuring the fluorescence of the ethidium homodimer (EthD-1) and Calcein AM...

... cellular organelles ER exosomes microparticles mitochondria Cellular organelles have their own critical functions. For example, mitochondria are a power source to maintain cellular and tissue energy demand. However, recent expansion of pharmacological, molecular and genetic tools have allowed us...

...Lisa Ayers; Rienk Nieuwland; Malcolm Kohler; Nicolle Kraenkel; Berne Ferry; Paul Leeson Interest in cell-derived microvesicles (or microparticles) within cardiovascular diagnostics and therapeutics is rapidly growing. Microvesicles are often measured in the circulation at a single time point...

...Jong-Shyan Wang; Ya-Lun Chang; Yi-Ching Chen; Hsing-Hua Tsai; Tieh-Cheng Fu Exercise and hypoxia paradoxically modulate vascular thrombotic risks. The shedding of procoagulant-rich microparticles from monocytes may accelerate the pathogenesis of atherothrombosis. The present study explores...

... was 3.1 %, a figure much lower than the value of 27% found by Brookes (1970) in a similar experiment. 3. The blood flow per unit mass to individual bones covered a wide range. Key words: bone blood flow, microparticles. Introduction Bone blood flow is a factor of importance in the study of mineral...

...R. Wootton 1. The uptake of an intra-arterial injection of 18 F was compared with the uptake of a simultaneous injection of 51 Cr-labelled microparticles in rabbit bone. 2. The mean single-passage extraction ratio of 18 F was 102% (sem 11%, n = 9) in the femur and 119% (sem 9%, n = 10) in the tibia...