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Keywords: mitochondrial dysfunction
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Clin Sci (Lond) (2019) 133 (18): 1993–2004.
Published: 24 September 2019
... Ritter; Felipe Dal-Pizzol Background: Several different mechanisms have been proposed to explain long-term cognitive impairment in sepsis survivors. The role of persisting mitochondrial dysfunction is not known. We thus sought to determine whether stimulation of mitochondrial dynamics improves...
Includes: Supplementary data
Clin Sci (Lond) (2016) 130 (17): 1511–1521.
Published: 18 July 2016
... design of effective strategies to delay or treat DCM. Mitochondrial dysfunction is recognized as the driving force for the pathogenesis of DCM; therefore, maintaining cardiac mitochondrial quality is crucial for DCM prevention. Mitophagy is the process by which cells degrade abnormal or superfluous...
Clin Sci (Lond) (2015) 129 (10): 851–862.
Published: 28 August 2015
... cardiomyopathy ER stress heart failure iron deficiency iron overload lipocalin 2 (Lcn2) mitochondrial dysfunction NGAL oxidative stress Iron is an essential micronutrient and its crucial role in many physiological functions is often underestimated [ 1 ]. Altered iron metabolism is implicated in a...
Clin Sci (Lond) (2007) 113 (12): 459–466.
Published: 14 November 2007
...José Magalhães; Rita Ferreira; Maria J. Neuparth; Paulo J. Oliveira; Franklim Marques; António Ascensão In the present study, the effect of vitamin E (α-tocopherol) on mice skeletal muscle mitochondrial dysfunction and oxidative damage induced by an in vivo acute and severe hypobaric hypoxic insult...