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Keywords: mitochondrial dysfunctionClose
Andressa Manfredini, Larissa Constantino, Milton Castro Pinto, Monique Michels, Henrique Burger, Luiza W. Kist, Milena Carvalho Silva, Lara Mezzari Gomes, Diogo Dominguini, Amanda Steckert, Carmen Simioni, Mauricio Bogo, Emílio Streck, Tatiana Barichello, João de Quevedo, Mervyn Singer, Cristiane Ritter, Felipe Dal-Pizzol
Clin Sci (Lond) (2019) 133 (18): 1993–2004.
Published: 24 September 2019
... Ritter; Felipe Dal-Pizzol Background: Several different mechanisms have been proposed to explain long-term cognitive impairment in sepsis survivors. The role of persisting mitochondrial dysfunction is not known. We thus sought to determine whether stimulation of mitochondrial dynamics improves...
Includes: Supplementary data
Clin Sci (Lond) (2016) 130 (17): 1511–1521.
Published: 18 July 2016
... design of effective strategies to delay or treat DCM. Mitochondrial dysfunction is recognized as the driving force for the pathogenesis of DCM; therefore, maintaining cardiac mitochondrial quality is crucial for DCM prevention. Mitophagy is the process by which cells degrade abnormal or superfluous...
Clin Sci (Lond) (2015) 129 (10): 851–862.
Published: 28 August 2015
... cardiomyopathy ER stress heart failure iron deficiency iron overload lipocalin 2 (Lcn2) mitochondrial dysfunction NGAL oxidative stress Iron is an essential micronutrient and its crucial role in many physiological functions is often underestimated [ 1 ]. Altered iron metabolism is implicated in a...
José Magalhães, Rita Ferreira, Maria J. Neuparth, Paulo J. Oliveira, Franklim Marques, António Ascensão
Clin Sci (Lond) (2007) 113 (12): 459–466.
Published: 14 November 2007
...José Magalhães; Rita Ferreira; Maria J. Neuparth; Paulo J. Oliveira; Franklim Marques; António Ascensão In the present study, the effect of vitamin E (α-tocopherol) on mice skeletal muscle mitochondrial dysfunction and oxidative damage induced by an in vivo acute and severe hypobaric hypoxic insult...