..., in part, to increased JNK activation and mitochondrial dysfunction. Correspondence: Firdos Ahmad ( [email protected] ) 06 10 2021 18 01 2022 20 01 2022 20 01 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022...

... 38. Wang Y. and Hekimi S. ( 2015 ) Mitochondrial dysfunction and longevity in animals: untangling the knot . Science 350 , 1204 – 1207 26785479 10.1126/science.aac4357 39. Klinge C.M. ( 2020 ) Estrogenic control of mitochondrial function . Redox Biol. 31...

... Ritter; Felipe Dal-Pizzol Background: Several different mechanisms have been proposed to explain long-term cognitive impairment in sepsis survivors. The role of persisting mitochondrial dysfunction is not known. We thus sought to determine whether stimulation of mitochondrial dynamics improves...

... design of effective strategies to delay or treat DCM. Mitochondrial dysfunction is recognized as the driving force for the pathogenesis of DCM; therefore, maintaining cardiac mitochondrial quality is crucial for DCM prevention. Mitophagy is the process by which cells degrade abnormal or superfluous...

... stress heart failure iron deficiency iron overload lipocalin 2 (Lcn2) mitochondrial dysfunction NGAL oxidative stress The normal range of circulating ferritin is from 30 μg/l to 300 μg/l. In healthy individuals, iron deficiency is defined when the circulating ferritin concentration falls...

...José Magalhães; Rita Ferreira; Maria J. Neuparth; Paulo J. Oliveira; Franklim Marques; António Ascensão In the present study, the effect of vitamin E (α-tocopherol) on mice skeletal muscle mitochondrial dysfunction and oxidative damage induced by an in vivo acute and severe hypobaric hypoxic insult...