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Keywords: mitogenic effects
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Aldo VENUTI, Debora SALANI, Alessia CIRILLI, Paola SIMEONE, Antonio MULLER, Silvio FLAMINI, Robert PADLEY, Anna BAGNATO
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 310S–313S.
Published: 01 September 2002
... receptor (ET B R) mRNA and do not secrete ET-1. In HPV-positive cancer cells, ET A R mediates the ET-1-induced mitogenic effect and sustains the basal growth rate of unstimulated cervical tumour cells. Therefore, ET-1 may be involved in the neoplastic growth of HPV-associated cervical carcinoma, where...
