... from plasma measurements of these metabolites in a number of clinical conditions (hypertension, cardiac failure, bilateral adrenalectomy and X-chromosomal deletions of the gene for monoamine oxidase), and before and during activation of sympathetic outflow or infusions of noradrenaline and adrenaline...

... synthetic enzymes rather than to an insensitivity of tyrosine hydroxylase to end-product inhibition. 4. The activities of the enzymes involved in catecholamine catabolism, monoamine oxidase and perhaps catecholamine O -methyltransferase, were reduced in phaeochromocytoma. This finding provides a biochemical...

...M. Iijima; Y. Kitamura; N. Yamamoto; H. Kawamura; T. Yasugi; M. Hatano 1. Intravenous administration of angiotensin II reduced the adrenaline content, increased the catechol- O -methyltransferase activity, and decreased the monoamine oxidase activity of the rat hypothalamus. 2. Intraventricularly...

...M. B. H. Youdim; D. G. Grahame-Smith; H. F. Woods 1. Monoamine oxidase activity in platelets prepared from the blood of patients with iron-deficiency anaemia was significantly lowered when compared with that in platelets from normal subjects. 2. The K m values of the platelet enzyme...

...B. H. Moussa; H. F. Woods; B. Mitchell; D. G. Grahame-Smith; Sheila Callender 1. The activity of monoamine oxidase, when assayed with four substrates, was significantly lowered in platelets prepared from the blood of patients with iron-deficiency anaemia. 2. Treatment with oral iron preparations...