... anticancer immune responses, very few have reached mainstream clinical use. A new approach introduced over the last few years is to use immunostimulatory mAbs (monoclonal antibodies) to boost weak endogenous antitumour immune responses to levels which are therapeutic. Such agonistic or antagonistic mAbs bind...

... of carbohydrate tumour-associated antigens by binding of lectins and antibodies, and puts it into the context of NMR fingerprints or signatures. © 1997 The Biochemical Society and the Medical Research Society 1997 cancer carbohydrate tumour antigens magnetic resonance spectroscopy monoclonal antibody...

... and conflict, and to discuss the methods adopted to circumvent the problems associated with analysis of the antibody response. autoantibodies autoimmunity B lymphocytes combinatorial library Graves' disease Hashimoto's thyroiditis monoclonal antibody repertoire development thyroglobulin thyroid...

... for probing the role of CGRP as an endogenous vasodilator. 2. The effects of an anti-CGRP monoclonal antibody (MAb; coded C4.19) and its Fab′ fragment on CGRP-induced changes in blood pressure and skin blood flow were studied in pentobarbitone-anaesthetized rats. Antidromic skin vasodilatation in the rat hind...

... Research Society 1970 immunoradiometric assay monoclonal antibody plasma renin concentration renin Clinical Science ( 1988) 75,669-672 669 Effects of frusemide and captopril on the relationship between biologically and immunologically active renin in human plasma JITSUO HIGAKI, TOSHIO OGIHARA...

...B. Pau; D. Simon; F. X. Galen; C. Devaux; F. Soubrier; J. Ménard; P. Corvol 1. A mouse hybridoma secreting an antibody directed against human renin was obtained by fusion of spleen cells with NS 1 myeloma cells. This monoclonal antibody recognizes human and monkey renins but neither hog nor mouse...