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Keywords: monocrotaline
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Articles

Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in mice

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Joseph George, Jie Sun, Jeanine D'Armiento
Journal: Clinical Science
Clin Sci (Lond) (2012) 122 (2): 83–92.
https://doi.org/10.1042/CS20110295
Published: 20 September 2011
... the decompensating features of MCT (monocrotaline)-induced PAH. Measurement of RV (right ventricular) pressure revealed a 2.5-fold increase after treatment with MCT, which was reduced to 1.5-fold in MMP-1 transgenic mice. There was conspicuous pulmonary inflammation with chronic infiltration of mononuclear cells...
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Articles

Magnesium aspartate hydrochloride attenuates monocrotaline-induced pulmonary artery hypertension in rats

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R. Mathew, E. S. Gloster, B. T. Altura, B. M. Altura
Journal: Clinical Science
Clin Sci (Lond) (1988) 75 (6): 661–667.
https://doi.org/10.1042/cs0750661
Published: 01 December 1988
...R. Mathew; E. S. Gloster; B. T. Altura; B. M. Altura 1. The effect of oral magnesium aspartate hydrochloride on monocrotaline (MCT)-induced pulmonary arterial hypertension was evaluated in rats. 2. A single subcutaneous injection of MCT, a pyrrolizidine alkaloid of plant origin, induces significant...
View articletitled, Magnesium aspartate hydrochloride attenuates monocrotaline-induced pulmonary artery hypertension in rats
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