... immune system, adipocyte dysfunction with insulin resistance, and low turnover bone disease. Higher blood levels of gut-derived uremic toxins are associated with increased cardiovascular events and mortality in the CKD population. Clinical trials that have examined interventions to trap toxic products...

... studies supporting the hypothesis that UA independently influences cardiovascular disease outcomes and mortality, a causal role is yet to be established. Serum UA is also considered as a useful biomarker for mortality in high-risk patients with acute coronary syndromes, heart failure and hypertension...

... outcome was 1-year all-cause mortality. The UA concentration [median (25th–75th quartiles)] was 6.44 mg/dl (5.40–7.70 mg/dl). There were 264 deaths (7.1%) during follow-up: 45 deaths in patients of the first UA quartile, 43 deaths in patients of the second UA quartile, 51 deaths in patients of the third...

...Paul Castillo Rodas; Olav Rooyackers; Christina Hebert; Åke Norberg; Jan Wernerman Glutamine depletion is demonstrated to be an independent predictor of hospital mortality in ICU (intensive care unit) patients. Today glutamine supplementation is recommended to ICU patients on parenteral nutrition...

... Biochemical Society 2010 adrenocorticotropic hormone (ACTH) aminoprocalcitonin peptide (N-PCT) cytokine mortality procalcitonin septic shock Sepsis and the closely related condition SIRS (systemic inflammatory syndrome) yearly affects 18 million people throughout the world [ 1 ]. In the U.K...

...Eva Tavares; Francisco J. Miñano Severe sepsis and septic shock are an important cause of mortality and morbidity. These illnesses can be triggered by the bacterial endotoxin LPS (lipopolysaccharide) and pro-inflammatory cytokines, particularly TNF-α (tumour necrosis factor-α) and IL (interleukin...

...Julio Núñez; Marifina Chilet; Juan Sanchis; Vicent Bodí; Eduardo Núñez; Gema Miñana; Nuria Tormo; Maria A. Clari; Mauricio Pellicer; Francisco J. Chorro; Angel Llàcer; David Navarro AHF (acute heart failure) causes significant morbidity and mortality. Recent studies have postulated...

.... In the present issue of Clinical Science , Zhang and co-workers prove that Chinese patients with high homocysteine levels have an increased risk of stroke recurrence and of all-cause mortality with respect to patients with lower levels. Remarkably, in their study, high homocysteine levels were associated...

...Weili Zhang; Kai Sun; Jinxing Chen; Yuhua Liao; Qin Qin; Aiqun Ma; Daowen Wang; Zhiming Zhu; Yibo Wang; Rutai Hui Plasma homocysteine concentrations have been associated with the risk of stroke, but its relevance to secondary vascular events and mortality after stroke remains unclear because...

... fluoroscopy, and baseline dyssynchrony was assessed by TDI (tissue Doppler imaging). The relationship between the LV lead position/dyssynchrony and mortality was compared using Kaplan–Meier curves, followed by Cox regression analysis. The all-cause and cardiovascular mortalities were 38 and 31% respectively...

...Gjin Ndrepepa; Siegmund Braun; Raisuke Iijima; Dritan Keta; Robert A. Byrne; Stefanie Schulz; Julinda Mehilli; Albert Schömig; Adnan Kastrati Although an association between elevated leucocyte count and mortality in patients with ACS (acute coronary syndromes) has been established, the independence...

...Jennifer H. Martin; Henry Krum HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors (statins) are well-established therapies in the prevention and treatment of cardiovascular disease, reducing all-cause mortality and cardiovascular events in many disease states. Studies have also suggested...

...Susan J. CARR; Sunita BAVANANDAN; Barbara FENTUM; Leong NG In the present study, we investigated the potential of N-BNP (N-terminal B-type natriuretic peptide) as a prognostic marker for risk of CV (cardiovascular) events, overall mortality and progression to ESRD (end-stage renal disease...

...Martin TEPEL; Markus VAN DER GIET; Alexander PARK; Walter ZIDEK Patients with end-stage renal disease show disturbances of calcium metabolism, including calcification of arterial walls. Such patients show increased mortality, in particular due to increased cardiovascular-associated deaths...

...-hypertensive agents cerebrovascular disorders coronary disease hypertension morbidity mortality Clinical Science and Molecular Medicine (1976) 51,645s-647~. Report on progress in the Australian National Blood Pressure Study (NBPS) J. D. A B E R N E T H Y , J . L. B A K E R , M. U . B U L L E N , M . L...

... hypertension mortality Clinical Science and Molecular Medicine (1976) 51, 649s-651s. Characteristics and prognosis for women with hypertension in a community: results of a longitudinal study in Goteborg, Sweden c. BENGTSSON A N D 0. L I N D Q U I S T Drpnrtnirnt Medicine, I I , Snhlgrcvi's Hospitnl...

... mortality was far higher in men than in women. 4. Causes of death were stroke in 17%, heart failure in 24%, coronary occlusion in 16%, uraemia in 4% and other diseases in 39%. At the first examination thirteen cases of malignant hypertension were registered, none at later sessions. © 1976 The Biochemical...

... and the Medical Research Society 1994 multi-centre randomized morbidity mortality myocardial infarct blood pressure measurement population screening drug treatment Clinical Science and Molecular Medicine (1973) 45,67s-70~. THE ORGANIZATION OF A MULTI-CENTRE RANDOMIZED CONTROL THERAPEUTIC TRIAL...