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Keywords: mouse model
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Clin Sci (Lond) (2016) 130 (1): 19–33.
Published: 30 November 2015
... understood. To investigate the postnatal role of VSMCs (vascular smooth muscle cells) EGFR in vivo and ex vivo , we generated a mouse model with cell-specific and inducible deletion of VSMC EGFR and studied the effect on basal blood pressure, acute pressure response to, among others, Ang II in vivo as well...
Includes: Supplementary data
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Clin Sci (Lond) (2014) 126 (11): 785–800.
Published: 13 February 2014
... and the caveolae-compartmentalized signalling have any role in AAA development has never been investigated. abdominal aortic aneurysm caveolae hypertension mouse model signalling mechanism vascular smooth muscle AngII was purchased from Sigma–Aldrich and Bachem. BAPN was purchased from TCI...
Includes: Supplementary data
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Clin Sci (Lond) (2014) 126 (8): 567–580.
Published: 08 December 2013
...) challenge of HDM-sensitized and challenged mice were insensitive to oral prednisone therapy. In summary we have described a CS-resistant mouse model mimicking the key aspects of viral asthma exacerbation using the clinically relevant aeroallergen HDM and the viral mimic poly(I:C). This model may provide...
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Clin Sci (Lond) (2007) 112 (6): 325–335.
Published: 12 February 2007
... glomerular basement membrane filtration barrier mouse model podocyte slit diaphragm Podocytes are highly differentiated epithelial cells that contribute to the size-selective nature of the glomerular filtration barrier (reviewed in [ 1 ]). Major processes extend from the cell body and branch out...