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Keywords: mucosal damage
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Articles
Endothelin-1 induces mucosal mast cell degranulation and tissue injury via ET A receptors
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 31S–34S.
Published: 01 September 2002
... mast cells and the degree of mucosal damage were determined in ileal biopsies. ET-1 induced dose-dependent alterations in the haemodynamic and morphological parameters, and caused significant mast cell degranulation. These changes were inhibited significantly by pretreatment with the ET A receptor...