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1-8 of 8
Keywords: multiple sclerosis
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Articles
Jennifer Kurz, Robert Brunkhorst, Christian Foerch, Leonard Blum, Marina Henke, Laureen Gabriel, Thomas Ulshöfer, Nerea Ferreirós, Michael J. Parnham, Gerd Geisslinger, Susanne Schiffmann
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (17): 1963–1976.
Published: 14 September 2018
... in a chain length-dependent manner. In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), we observed that the genetic deletion of CerS2 suppresses EAE pathology by interaction with granulocyte-colony stimulating factor (G-CSF) signaling and CXC motif chemokine...
Includes: Supplementary data
Articles
Othman Al-Sawaf, Tim Clarner, Athanassios Fragoulis, Yuet Wai Kan, Thomas Pufe, Konrad Streetz, Christoph Jan Wruck
Journal:
Clinical Science
Clin Sci (Lond) (2015) 129 (12): 989–999.
Published: 18 September 2015
... of a large battery of cytoprotective genes, it plays a crucial role in the prevention of degenerative disease in multiple organs. Thus it has been the focus of research as a pharmacological target that could be used for prevention and treatment of chronic diseases such as multiple sclerosis, chronic kidney...
Articles
Gabriella Ruocco, Silvia Rossi, Caterina Motta, Giulia Macchiarulo, Francesca Barbieri, Marco De Bardi, Giovanna Borsellino, Annamaria Finardi, Maria Grazia Grasso, Serena Ruggieri, Claudio Gasperini, Roberto Furlan, Diego Centonze, Luca Battistini, Elisabetta Volpe
Journal:
Clinical Science
Clin Sci (Lond) (2015) 129 (4): 291–303.
Published: 21 May 2015
...Gabriella Ruocco; Silvia Rossi; Caterina Motta; Giulia Macchiarulo; Francesca Barbieri; Marco De Bardi; Giovanna Borsellino; Annamaria Finardi; Maria Grazia Grasso; Serena Ruggieri; Claudio Gasperini; Roberto Furlan; Diego Centonze; Luca Battistini; Elisabetta Volpe Multiple sclerosis (MS...
Includes: Supplementary data
Articles
Alessandra de Paula A. Sousa, Kelen C. R. Malmegrim, Rodrigo A. Panepucci, Doralina S. Brum, Amilton A. Barreira, Antonio Carlos Dos Santos, Amélia G. Araújo, Dimas Tadeu Covas, Maria C. Oliveira, Daniela A. Moraes, Fabiano Pieroni, George M. Barros, Belinda P. Simões, Richard Nicholas, Richard K. Burt, Júlio C. Voltarelli, Paolo A. Muraro
Journal:
Clinical Science
Clin Sci (Lond) (2015) 128 (2): 111–120.
Published: 19 September 2014
.... Burt; Júlio C. Voltarelli; Paolo A. Muraro Autologous haematopoietic stem-cell transplantation (AHSCT) has been experimented as a treatment in patients affected by severe forms of multiple sclerosis (MS) who failed to respond to standard immunotherapy. The rationale of AHSCT is to ‘reboot’ the immune...
Includes: Supplementary data
Articles
Verónica Valero-Esquitino, Kristin Lucht, Pawel Namsolleck, Florianne Monnet-Tschudi, Tobias Stubbe, Franziska Lucht, Meng Liu, Friederike Ebner, Christine Brandt, Leon A. Danyel, Daniel C. Villela, Ludovit Paulis, Christa Thoene-Reineke, Björn Dahlöf, Anders Hallberg, Thomas Unger, Colin Sumners, U. Muscha Steckelings
Journal:
Clinical Science
Clin Sci (Lond) (2015) 128 (2): 95–109.
Published: 05 September 2014
...; U. Muscha Steckelings In the present study, we evaluated stimulation of the angiotensin type 2 receptor (AT 2 R) by the selective non-peptide agonist Compound 21 (C21) as a novel therapeutic concept for the treatment of multiple sclerosis using the model of experimental autoimmune encephalomyelitis...
Articles
Kai-Chen Wang, Ching-Piao Tsai, Chao-Lin Lee, Shao-Yuan Chen, Gu-Jiun Lin, Mao-Hsiung Yen, Huey-Kang Sytwu, Shyi-Jou Chen
Journal:
Clinical Science
Clin Sci (Lond) (2013) 125 (7): 329–340.
Published: 07 June 2013
... augment the production of PPAR-γ in vivo and modulate adaptive immunity both centrally and peripherally in EAE and may reveal further antioxidative and immunomodulatory mechanisms for the application of ALA in human MS (multiple sclerosis). © The Authors Journal compilation © 2013 Biochemical Society...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1997) 93 (6): 479–491.
Published: 01 December 1997
... it seems likely that most autoimmune diseases are polygenic with no single gene being either necessary or sufficient for disease development. Of the organ-specific autoimmune diseases, genome screens have now been completed in insulin-dependent diabetes mellitus and multiple sclerosis. Furthermore...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1997) 92 (2): 113–122.
Published: 01 February 1997
...Richard Milner 1. Multiple sclerosis is characterized by areas of demyelination spread throughout the central nervous system, in which the myelin sheaths surrounding axons are destroyed. While therapies aimed at suppressing the autoimmune response, such as β-interferon, may prevent further damage...
