... evaluation of myofibrillar protein degradation, which appears to be remarkably increased in cirrhotic patients. The relevance of increased myofibrillar protein turnover in muscle wasting of subjects with advanced cirrhosis remains to be determined. cirrhosis creatinine 3-methylhistidine muscle protein...

.... Firm conclusions cannot, however, be drawn without confirmatory, direct measurement of the breakdown rates of muscle protein in vivo. 11 12 1979 16 5 1980 © 1980 The Biochemical Society and the Medical Research Society 1980 creatinine enterocutaneous fistula N τ...