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Keywords: mycophenolic acid
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Articles

Binding of anti-dsDNA antibodies to proximal tubular epithelial cells contributes to renal tubulointerstitial inflammation

Susan Yung, Claudia Y.C. Ng, Kin Yi Au, Kwok Fan Cheung, Qing Zhang, Chenzhu Zhang, Desmond Y.H. Yap, Mel K.M. Chau, Tak Mao Chan
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (1): 49–67.
https://doi.org/10.1042/CS20160421
Published: 09 December 2016
... protein-1 (MCP-1) in patients. Binding of anti-dsDNA Abs to HK-2 cells was investigated by cellular ELISA, flow cytometry and immunohistochemistry. IL-6, IL-8 and MCP-1 secretion, mitogen-activated protein kinase (MAPK) activation and the effect of mycophenolic acid (MPA) were investigated by ELISAs...
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Articles

Mycophenolate mofetil treatment following renal transplantation decreases GTP concentrations in mononuclear leucocytes

Piotr JAGODZINSKI, Slawomir LIZAKOWSKI, Ryszard T. SMOLENSKI, Ewa M. SLOMINSKA, David GOLDSMITH, H. Anne SIMMONDS, Boleslaw RUTKOWSKI
Journal: Clinical Science
Clin Sci (Lond) (2004) 107 (1): 69–74.
https://doi.org/10.1042/CS20030332
Published: 23 June 2004
... mycophenolic acid purine nucleotide pyrimidine nucleotide The elevation in erythrocyte GTP in MMF-treated patients raised the distinct possibility that, if long-term MMF therapy were to induce IMPDH activity, then antirejection protection would eventually become less effective. Clearly, our present...
View article titled, Mycophenolate mofetil treatment following renal transplantation decreases GTP concentrations in mononuclear leucocytes
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Articles

The immunosuppressive drug mycophenolic acid reduces endothelin-1 synthesis in endothelial cells and renal epithelial cells

Cornelia HAUG, Alexandra SCHMID-KOTSAS, Theresia LINDER, Peter M. JEHLE, Max G. BACHEM, Adolf GRUENERT, Eva ROZDZINSKI
Journal: Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 76S–80S.
https://doi.org/10.1042/CS103S076S
Published: 01 September 2002
... A (CsA)- and tacrolimus-associated nephrotoxicity. This study aimed to investigate whether the new immunosuppressive drug mycophenolic acid (MPA), which in contrast with CsA and tacrolimus lacks nephrotoxic side effects, modulates ET-1 synthesis in endothelial cells and renal epithelial cells. ET-1...
View article titled, The immunosuppressive drug <span class="search-highlight">mycophenolic</span> <span class="search-highlight">acid</span> reduces endothelin-1 synthesis in endothelial cells and renal epithelial cells
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