...Sammy W. M. Shiu; Su-Mei Xiao; Ying Wong; Wing-Sun Chow; Karen S. L. Lam; Kathryn C.B. Tan LDL (low-density lipoprotein) is subjected to pro-atherogenic modifications in the circulation. A novel uraemia-independent mechanism of carbamylation of lipoproteins mediated by MPO (myeloperoxidase) has...

... is properly cited. myeloperoxidase myocardial infarction neutrophil peptide prognosis proteinase 3 Atherosclerosis is associated with inflammatory changes in the blood vessel wall [ 1 ], including macrophage and lymphocyte infiltration. There is an association between neutrophil count...

...Sanjeev Sirpal There is an emerging and significant body of research that suggests that MPO (myeloperoxidase) may be a critical mediator in dysfunctional lipoprotein formation and, hence, atherogenic initiation and progression. MPO is a haem peroxidase found in leucocytes and is abundant...

... with ulcerative colitis and 21 patients with Crohn's disease. Biliary lactoferrin and myeloperoxidase concentrations were quantified by ELISA. 3. In active ulcerative colitis, the mean lactoferrin concentration in gall bladder bile of 2.8±0.40 ;mg/l was higher than that seen after colectomy (1.2±0.11 ;mg/l; P...

... of the inflammatory response to exercise were measured: polymorphonuclear myeloperoxidase (MPO), anaphylatoxin C5a (C5a), tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6). Plasma endotoxin was measured by a sensitive and rapid chromogenic Limulus assay. All inflammatory markers were significantly increased...

...A. D. Dwarakanath; I. A. Finnie; C. M. Beesley; G. M. O'Dowd; J. Nash; H. H. Tsai; N. Parker; Jonathan M. Rhodes 1. Faecal excretion of the leucocyte primary granule component, myeloperoxidase, and of the secondary granule component, lactoferrín, were compared in inflammatory bowel disease...

... in a rapid loss of anti-elastase activity which paralleled that of the antitrypsin activity, suggesting that both inhibitor activities are represented by the same active site. 3. The myeloperoxidase-oxidizing system was found to be responsible for the inactivation of ALP. 4. The oxidized inhibitor was unable...