... chemokines heart failure myocardial infarction myocarditis transplant coronary artery disease Death rates from cardiovascular diseases (CVDs) have declined, yet the burden remains high. It has been estimated that 17.5 million people globally died from CVDs in 2012 [ 1 ], and it has been computed...

... are expressed in other tissues such as those of the cardiovascular system. In the present review, the role of TLRs in septic cardiomyopathy, viral myocarditis, atherosclerosis, ischaemia/reperfusion injury and cardiac remodelling after myocardial infarction are outlined, with attention paid to genetically...

... on the development of murine acute myocarditis caused by CVB3 (coxsackievirus B3) were analysed. Olmesartan and a non-specific vasodilator hydralazine lowered systolic blood pressure of mice on day 7 after virus inoculation to a similar extent. Olmesartan significantly decreased myocardial inflammation compared...

...Mamoru SATOH; Motoyuki NAKAMURA; Tomonari AKATSU; Junji IWASAKA; Yudai SHIMODA; Ikuo SEGAWA; Katsuhiko HIRAMORI Previous studies have demonstrated that inflammatory cytokine expression associated with enteroviral (EV) infection may play an important role in human myocarditis. However, the mechanism...

... autoimmune myocarditis (EAM) have not yet been determined. To investigate gene expression in the myocardium of EAM, absolute copy numbers of 44 mRNA species [calcium-handling proteins, contractile proteins, natriuretic peptides (NPs), cytokines, chemokines, growth factors, renin–angiotensin–aldosterone (RAA...