... myocardium proteomics References 1. Lippi G. , Sanchis-Gomar F. and Cervellin G. ( 2021 ) Global epidemiology of atrial fibrillation: An increasing epidemic and public health challenge . Int. J. Stroke: Off. J. Int. Stroke Soc. 16 , 217 – 221 10.1177...

... mechanisms underlying cardiac aging. Aging promotes structural and functional changes in the atria, ventricles, valves, myocardium, pericardium, the cardiac conduction system, and the vasculature. We highlight the factors known to accelerate and attenuate the intrinsic aging of the heart and vessels...

... to the capillary endothelium at any given time (see for review [ 8 ]). diabetes fatty acid utilization heart failure metabolism myocardium triglycerides The average human heart beats over 2.5 billion times in a lifetime. Every single beat requires contraction of the ventricular and atrial...

...). published by Portland Press Limited on behalf of the Biochemical Society 2016 large intervening non-coding RNA myocardium non-coding RNA skeletal muscle therapeutics Perhaps one of the least understood aspects of lncRNAs is how these molecules influence cellular processes. Adding...

... The Authors Journal compilation © 2009 Biochemical Society 2009 limb ischaemia myocardium mitogen-activated protein kinase (MAPK) opioid protein kinase C (PKC) remote ischaemic preconditioning The phenomenon of IPC (ischaemic preconditioning), induced by short periods of ischaemia...

... manner. Correspondence: Dr Jorge Berlanga (email [email protected] ). 4 5 2006 7 9 2006 21 9 2006 21 9 2006 The Biochemical Society 2007 cardioprotection growth-hormone-releasing peptide 6 (GHRP6) infarction ischaemia myocardium necrosis...

... could, in principle, be used to recreate the embryonic state and achieve coupled myocardial and coronary vascular regeneration in failing hearts. There is relatively little controversy, however, regarding the creation of new cardiac myocytes during mammalian embryonic development. The myocardium...

... and protein expression was determined in the right atrial myocardium of New York Heart Association class I patients and class IV patients undergoing aorto-coronary bypass surgery. ECE-1 mRNA was upregulated in failing atrial myocardium. Furthermore, ET-1 peptide levels were increased in failing atrial...

... the neovessels of the channel scars, has the potential for improved clinical outcome. Correspondence : Dr X. Mueller (e-mail [email protected] ). 20 4 2000 21 7 2000 9 8 2000 The Biochemical Society and the Medical Research Society © 2000 2000 laser myocardium...

...Mohamed K. AL-OBAIDI; Philip J. ETHERINGTON; David J. BARRON; Peter C. WINLOVE; John R. PEPPER The supply and utilization of oxygen by the myocardium reflect the dynamic efficiency of the microcirculation. The present study examines these parameters during coronary artery bypass surgery. We used...

... levels were similar in both groups (2.09±0.44 and 1.95±0.52 ng/ml in groups I and II respectively). We suggest that: (1) minor degrees of myocardial ischaemic damage result in release of ADM by the heart, and (2) ADM may play a protective role in the myocardium during an ischaemic insult. This suggests...

... myocardium, and to investigate the hypothesis that alterations in the quantity and patterns of expression of myocardial gap junctions occur in ischaemic and hypertrophic myocardial disease. 2. An antibody raised against connexin43 was used for immunohistochemical labelling of myocardium examined by confocal...

... 11 5 1994 9 6 1994 © 1994 The Biochemical Society and the Medical Research Society 1994 heart muscle lipopolysaccharide messenger RNA myocardium myosin protein synthesis sepsis Clinical Science (1994) 87, 535446 (Printed in Great Britain) Cardiac muscle protein gene...

... and the Medical Research Society 1994 cystic fibrosis electrocardiography myocardium signal variability Clinical Science (1994) 87, 103-107 (Printed in Great Britain) I03 Signal variance electrocardiogram: a test for early detection of myocardial involvement in cystic fibrosis? Ulla FREYSCHUSS*, Lena...

... Society 1990 arrhythmias electrocardiogram hyperkalemia intraventricular conduction monophasic action potential myocardium Clinical Science (1990) 78, 17-24 17 Monophasic action potential recordings in response to rapid transient elevation of extracellular potassium and their modification...

...-angiotensin-aldosterone axis under hypoxic conditions. Correspondence: Dr R. J. D. Winter, Department of Medicine (Respiratory Division), Hammersmith Hospital, Du Cane Road, London W 12 OHS. Key words: anoxia, atrial natriuretic peptide, myocardium. Abbreviations: ANP, atrial natriuretic peptide; Ftoz, frac...

...M. K. Davies; P. Cummins; W. A. Littler 1. Electrophoretic and enzyme techniques have been used to study the structure and function of the contractile protein system in the myocardium of dogs before and after β-adrenoceptor blockade. Animals were examined after acute β-adrenoceptor blockade...

... 12 1982 19 1 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 distal tubule blockade glomerular filtration rate kidney myocardium renal blood flow sodium excretion urine flow urine osmolality Clinical Science (1983) 65, 47-55 Effect of atrial...

..., indicating inhibition of the sodium pump, could not be dissociated from the positive inotropic effect of ouabain. 4. The greater sensitivity to ouabain of human myocardium in vivo (10 −8 mol/l) than in vitro (10 −7 mol/l) may be due to cellular changes occurring in isolated preparations. 16 2 1979...

...P. A. Poole-Wilson; S. M. Cobbe; C. H. Fry 1. We have studied the acute effects of frusemide, triamterene and amiloride on potassium exchange, the action potential and mechanical function of isolated rabbit myocardium. 2. Potassium exchange in the myocardium was unaltered by these diuretics. 3...

...F. J. Bloomfield; G. Wells; E. Welman; T. J. Peters 1. Homogenates of guinea-pig left ventricle were fractionated by differential pelleting and by centrifugation on continuous sucrose density gradients. 2. The principal subcellular organelles of myocardium, characterized by their marker enzyme...

...P. A. Poole-Wilson 1. The efflux of 14 C-Iabelled 5,5-dimethyl-2,4-oxazolidinedione (DMO) from the myocardium of the rabbit has been studied. The perfusate pH was 7·38. 2. The effluent curve is complex and appears to be the resultant of movement between at least four compartments. 3. The first two...