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Keywords: myocardium
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Articles
Clin Sci (Lond) (2018) 132 (13): 1367–1382.
Published: 09 July 2018
... mechanisms underlying cardiac aging. Aging promotes structural and functional changes in the atria, ventricles, valves, myocardium, pericardium, the cardiac conduction system, and the vasculature. We highlight the factors known to accelerate and attenuate the intrinsic aging of the heart and vessels...
Articles
Clin Sci (Lond) (2017) 131 (16): 2079–2094.
Published: 24 July 2017
... utilization heart failure metabolism myocardium triglycerides The average human heart beats over 2.5 billion times in a lifetime. Every single beat requires contraction of the ventricular and atrial cardiomyocytes, which rely on ATP breakdown to power both myofibrillar shortening and the movement...
Articles
Clin Sci (Lond) (2016) 130 (24): 2245–2256.
Published: 04 November 2016
...). published by Portland Press Limited on behalf of the Biochemical Society 2016 large intervening non-coding RNA myocardium non-coding RNA skeletal muscle therapeutics It has been predicted that >75% of the entire human genome is transcribed into RNA, however only approximately 2–3% codes...
Articles
Clin Sci (Lond) (2009) 117 (5): 191–200.
Published: 03 August 2009
... (email andrew.redington@sickkids.ca ). 9 10 2008 16 1 2009 28 1 2009 28 1 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 limb ischaemia myocardium mitogen-activated protein kinase (MAPK) opioid protein kinase C (PKC) remote ischaemic...
Articles
Clin Sci (Lond) (2007) 112 (4): 241–250.
Published: 17 January 2007
... episode in relation to expression in intact hearts ( P <0.01). In conclusion, GHRP6 exhibits antioxidant effects which may partially contribute to reduce myocardial ischaemic damage. cardioprotection growth-hormone-releasing peptide 6 (GHRP6) infarction ischaemia myocardium necrosis...
Articles
Clin Sci (Lond) (2006) 111 (1): 35–46.
Published: 14 June 2006
... The Biochemical Society 2006 There is relatively little controversy, however, regarding the creation of new cardiac myocytes during mammalian embryonic development. The myocardium is initially formed from cardiomyocyte progenitor cells in primary and secondary heart fields (reviewed in [ 14 – 16...
Articles
Clin Sci (Lond) (2002) 103 (s2002): 237S–240S.
Published: 01 September 2002
... and protein expression was determined in the right atrial myocardium of New York Heart Association class I patients and class IV patients undergoing aorto-coronary bypass surgery. ECE-1 mRNA was upregulated in failing atrial myocardium. Furthermore, ET-1 peptide levels were increased in failing atrial...
Articles
Clin Sci (Lond) (2000) 99 (6): 535–540.
Published: 15 November 2000
... the neovessels of the channel scars, has the potential for improved clinical outcome. laser myocardium revascularization Correspondence : Dr X. Mueller (e-mail Xavier.Mueller@chuv.hospvd.ch ). 20 4 2000 21 7 2000 9 8 2000 The Biochemical Society and the Medical Research...
Articles
Clin Sci (Lond) (2000) 98 (3): 321–328.
Published: 10 February 2000
...Mohamed K. AL-OBAIDI; Philip J. ETHERINGTON; David J. BARRON; Peter C. WINLOVE; John R. PEPPER The supply and utilization of oxygen by the myocardium reflect the dynamic efficiency of the microcirculation. The present study examines these parameters during coronary artery bypass surgery. We used...
Articles
Clin Sci (Lond) (1999) 96 (4): 415–420.
Published: 01 April 1999
... levels were similar in both groups (2.09±0.44 and 1.95±0.52 ng/ml in groups I and II respectively). We suggest that: (1) minor degrees of myocardial ischaemic damage result in release of ADM by the heart, and (2) ADM may play a protective role in the myocardium during an ischaemic insult. This suggests...
Articles
Clin Sci (Lond) (1996) 90 (6): 447–452.
Published: 01 June 1996
... myocardium, and to investigate the hypothesis that alterations in the quantity and patterns of expression of myocardial gap junctions occur in ischaemic and hypertrophic myocardial disease. 2. An antibody raised against connexin43 was used for immunohistochemical labelling of myocardium examined by confocal...
Articles
Clin Sci (Lond) (1994) 87 (5): 539–546.
Published: 01 November 1994
... 11 5 1994 9 6 1994 © 1994 The Biochemical Society and the Medical Research Society 1994 heart muscle lipopolysaccharide messenger RNA myocardium myosin protein synthesis sepsis Clinical Science (1994) 87, 535446 (Printed in Great Britain) Cardiac muscle protein gene...
Articles
Clin Sci (Lond) (1994) 87 (1): 103–107.
Published: 01 July 1994
... and the Medical Research Society 1994 cystic fibrosis electrocardiography myocardium signal variability Clinical Science (1994) 87, 103-107 (Printed in Great Britain) I03 Signal variance electrocardiogram: a test for early detection of myocardial involvement in cystic fibrosis? Ulla FREYSCHUSS*, Lena...
Articles
Clin Sci (Lond) (1990) 78 (1): 17–24.
Published: 01 January 1990
... potential myocardium © 1990 The Biochemical Society and the Medical Research Society 1990 2 6 1989 26 6 1989 Clinical Science (1990) 78, 17-24 17 Monophasic action potential recordings in response to rapid transient elevation of extracellular potassium and their modification...
Articles
Clin Sci (Lond) (1989) 76 (1): 95–101.
Published: 01 January 1989
... 1988 © 1989 The Biochemical Society and the Medical Research Society 1989 anoxia atrial natriuretic peptide myocardium Clinical Science (1989) 76, 95-10 I Atrial natriuretic peptide levels in plasma and in cardiac tissues after chronic hypoxia in rats R. J. D. WINTER, L. MELEAGROS, S...
Articles
Clin Sci (Lond) (1984) 67 (2): 259–267.
Published: 01 August 1984
...M. K. Davies; P. Cummins; W. A. Littler 1. Electrophoretic and enzyme techniques have been used to study the structure and function of the contractile protein system in the myocardium of dogs before and after β-adrenoceptor blockade. Animals were examined after acute β-adrenoceptor blockade...
Articles
Clin Sci (Lond) (1983) 65 (1): 47–55.
Published: 01 July 1983
... 12 1982 19 1 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 distal tubule blockade glomerular filtration rate kidney myocardium renal blood flow sodium excretion urine flow urine osmolality Clinical Science (1983) 65, 47-55 Effect of atrial...
Articles
Clin Sci (Lond) (1979) 57 (5): 415–420.
Published: 01 November 1979
..., indicating inhibition of the sodium pump, could not be dissociated from the positive inotropic effect of ouabain. 4. The greater sensitivity to ouabain of human myocardium in vivo (10 −8 mol/l) than in vitro (10 −7 mol/l) may be due to cellular changes occurring in isolated preparations. 16 2 1979...
Articles
Clin Sci Mol Med (1978) 55 (6): 555–559.
Published: 01 December 1978
...P. A. Poole-Wilson; S. M. Cobbe; C. H. Fry 1. We have studied the acute effects of frusemide, triamterene and amiloride on potassium exchange, the action potential and mechanical function of isolated rabbit myocardium. 2. Potassium exchange in the myocardium was unaltered by these diuretics. 3...
Articles
Clin Sci Mol Med (1977) 53 (1): 63–74.
Published: 01 July 1977
...F. J. Bloomfield; G. Wells; E. Welman; T. J. Peters 1. Homogenates of guinea-pig left ventricle were fractionated by differential pelleting and by centrifugation on continuous sucrose density gradients. 2. The principal subcellular organelles of myocardium, characterized by their marker enzyme...
Articles
Clin Sci Mol Med (1976) 51 (2): 197–201.
Published: 01 August 1976
...P. A. Poole-Wilson 1. The efflux of 14 C-Iabelled 5,5-dimethyl-2,4-oxazolidinedione (DMO) from the myocardium of the rabbit has been studied. The perfusate pH was 7·38. 2. The effluent curve is complex and appears to be the resultant of movement between at least four compartments. 3. The first two...