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Keywords: neurogenesis
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Clin Sci (Lond) (2019) 133 (14): 1603–1607.
Published: 22 July 2019
...–1386) provides a possible explanation for the underlying mechanisms of poor long-term motor recovery after stroke in obesity-induced diabetes animal model. Authors report that stroke-induced neurogenesis and parvalbumin (PV)+ interneuron-mediated neuroplasticity is severely impaired due to obesity...
Clin Sci (Lond) (2017) 131 (2): 123–138.
Published: 23 December 2016
...Veronica Begni; Marco Andrea Riva; Annamaria Cattaneo Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection. The BDNF gene structure is very complex and consists of multiple 5...
Clin Sci (Lond) (2012) 122 (10): 473–483.
Published: 26 January 2012
... a diabetic patient on Ex-4 therapy. Furthermore, we investigated inflammation and neurogenesis as potential cellular mechanisms underlying the Ex-4 efficacy. A total of seven 9-month-old Type 2 diabetic Goto–Kakizaki rats were treated peripherally for 4 weeks with Ex-4 at 0.1, 1 or 5 μg/kg of body weight...
Clin Sci (Lond) (2011) 121 (9): 367–387.
Published: 12 July 2011
... on non-infectious CNS diseases/injury. In particular, TLRs recognize a number of endogenous molecules liberated from damaged tissues and, as such, influence inflammatory responses during tissue injury and autoimmunity. In addition, recent studies have implicated TLR involvement during neurogenesis...
Clin Sci (Lond) (2006) 111 (3): 171–183.
Published: 15 August 2006
... haemodynamic steal phenomena with reduced blood flow in ischaemic areas and increased flow outside the MCA territory, again suggesting that VEGF overexpression might worsen cerebral reperfusion after stroke. angiogenesis angiogenic factor endothelial cell ischaemic stroke neurogenesis penumbra...