... hypertension brain prorenin up-regulation has been claimed, which would generate angiotensin following its binding to the (pro)renin receptor. However, recent studies reported no evidence for prorenin expression in the brain, nor for its selective up-regulation in neurogenic hypertension, and the (pro)renin...

... subserving a cardiovascular function and for greater use of morphological techniques to confirm the reliability of biochemical and physiological experiments in the central nervous system. Two appropriate techniques are described. 3. Models of experimental hypertension. (a) Neurogenic hypertension...

... Society and the Medical Research Society 1978 essential hypertension neurogenic hypertension peripheral vasodilatation plasma renin activity prazosin Clinical Science and Molecular Medicine (1978) 55,337s-339s Effects of prazosin on blood pressure:and plasma renin activity in man J . R O S E...

...John L. Reid; Peter J. Lewis; Colin T. Dollery 1. The role of the central nervous system (CNS) in maintaining arterial pressure was investigated in two types of experimental hypertension in rabbits. 2. In rabbits with neurogenic hypertension produced by baroreceptor denervation, anaesthesia...

... in essential hypertension is at least in part due to excess of sympathetic activity. © 1994 The Biochemical Society and the Medical Research Society 1994 essential hypertension plasma noradrenaline neurogenic hypertension Clinical Science and Molecular Medicine (1973) 45, 119s-121s. SYMPATHETIC...