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Keywords: neuroinflammation
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Clin Sci (Lond) (2020) 134 (15): 2075–2090.
Published: 13 August 2020
... the activation of microglia in MPTP PD model by restoring CD200-CD200R signal inhibit microglia mediated neuroinflammation and the differentiation of T cells to Th17. Correspondence: Zhaoliang Su ( szl30@ujs.edu.cn ) 05 05 2020 21 07 2020 23 07 2020 24 07 2020 © 2020 The Author...
Clin Sci (Lond) (2020) 134 (13): 1677.
Published: 07 July 2020
... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . microglia M1/M2 sepsis neuroinflammation The authors of the original article “Modulation of microglial phenotypes improves sepsis-induced hippocampus-dependent cognitive...
Clin Sci (Lond) (2020) 134 (7): 765–776.
Published: 07 April 2020
.... Conclusions: GdCl 3 and IL-4 are able to manipulate microglial phenotype in an animal models of sepsis, by increasing the polarization toward an M2 phenotype IL-4 and GdCl 3 treatment was associated with decreased brain inflammation and functional recovery. M1/M2 microglia neuroinflammation sepsis...
Clin Sci (Lond) (2020) 134 (5): 547–570.
Published: 13 March 2020
... play a role in inflammation. In this review, we try to elucidate the connections between peripheral inflammation at obesity and Type 2 diabetes and the central inflammatory process. Multiple lines of evidence highlight the importance of peripheral inflammation and its link to neuroinflammation, which...
Clin Sci (Lond) (2017) 131 (6): 425–437.
Published: 06 March 2017
... the response of stiffened blood vessels in times of increased metabolic need. Intermittent hypoxia/ischaemia activates a molecular injury cascade, producing an incomplete infarction that is most damaging to the deep WM, which is a watershed region for cerebral blood flow. Neuroinflammation caused by hypoxia...
Clin Sci (Lond) (2015) 128 (2): 95–109.
Published: 05 September 2014
... multiple sclerosis neuroinflammation neuroprotection new therapies • Since the AT 2 R had been shown to act through anti-inflammatory and neuroprotective effects, we decided to test the effect of direct pharmacological stimulation of the AT 2 R in EAE in mice, which is a model of MS, i.e...