... the activation of microglia in MPTP PD model by restoring CD200-CD200R signal inhibit microglia mediated neuroinflammation and the differentiation of T cells to Th17. Correspondence: Zhaoliang Su ( szl30@ujs.edu.cn ) 05 05 2020 21 07 2020 23 07 2020 24 07 2020 © 2020 The Author...

... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . microglia M1/M2 sepsis neuroinflammation The authors of the original article “Modulation of microglial phenotypes improves sepsis-induced hippocampus-dependent cognitive...

.... Conclusions: GdCl 3 and IL-4 are able to manipulate microglial phenotype in an animal models of sepsis, by increasing the polarization toward an M2 phenotype IL-4 and GdCl 3 treatment was associated with decreased brain inflammation and functional recovery. M1/M2 microglia neuroinflammation sepsis...

... play a role in inflammation. In this review, we try to elucidate the connections between peripheral inflammation at obesity and Type 2 diabetes and the central inflammatory process. Multiple lines of evidence highlight the importance of peripheral inflammation and its link to neuroinflammation, which...

... the response of stiffened blood vessels in times of increased metabolic need. Intermittent hypoxia/ischaemia activates a molecular injury cascade, producing an incomplete infarction that is most damaging to the deep WM, which is a watershed region for cerebral blood flow. Neuroinflammation caused by hypoxia...

... multiple sclerosis neuroinflammation neuroprotection new therapies • Since the AT 2 R had been shown to act through anti-inflammatory and neuroprotective effects, we decided to test the effect of direct pharmacological stimulation of the AT 2 R in EAE in mice, which is a model of MS, i.e...