...Christine Maric-Bilkan Vascular complications are a leading cause of morbidity and mortality in both men and women with type 1 (T1DM) or type 2 (T2DM) diabetes mellitus, however the prevalence, progression and pathophysiology of both microvascular (nephropathy, neuropathy and retinopathy...

... to the neural and vascular complications of experimental diabetes; LY333531 is a candidate for further study in clinical trials of diabetic neuropathy and vasculopathy. Correspondence : Dr Norman E. Cameron (e-mail [email protected] ). 28 3 2002 6 6 2002 The Biochemical Society...

...Paetrick M. Netten; Hub Wollersheim; Theo Thien; Jos A. Lutterman 1. In the feet of patients with diabetic neuropathy, total skin blood flow is increased due to an increased shunt flow. The question is, does this increased anastomotic shunt flow lead to either under- or overperfused nutritive...

...S. J. Benbow; D. W. Pryce; K. Noblett; I. A. MacFarlane; P. S. Friedmann; G. Williams 1. Flow motion is the cyclical variation in blood flow owing to the rhythmical opening and closing of arterioles. Previous studies have suggested that cutaneous flow motion may be altered in diabetic neuropathy...

... develop before clinical large-fibre neuropathy and could itself predispose to foot complications. © 1991 The Biochemical Society and the Medical Research Society 1991 hyperaemia injury insulin-dependent (Type 1) diabetes mellitus laser Doppler flowmetry neuropathy Clinical Science (1991...

... diabetic neuropathy. This excess shunt flow and its local neurogenic control may be important in the development of complications of the neuropathic limb. 2. The response of arteriovenous anastomoses to local heating was assessed in 13 diabetic patients with neuropathy (12 insulin-dependent), 10 diabetic...

... kinetics leucocytes myo inositol neuropathy ouabain sodium Clinical Science ( 1 990) 78,335-341 335 ' myo-Inositsl influx into human leucocytes: methods of measurement and the effect of glucose D. SIMMONS, J. BOMFORD AND L. L. NG Sheikh Rashid Diabetes Unit and University Department of Clinical...

... diabetic patients [Kronert, K., Hulsen, J., Luft, D., Stetter, T. & Eggstein, M. ( 1987) Journal of Clinical Endocrinology and Metabolism, 64,12 19-12231. Key words: calcitonin-gene-related peptide, diabetes, insulin, myenteric plexus, neurofilaments, neuropathy, phosphorylation, vasoactive intestinal...

... (NA) were measured in eight healthy subjects and 12 long-term insulin-dependent diabetic patients with and without autonomic neuropathy, before and after intravenous infusion of the ganglionic blocking agent trimethaphan camsylate, in order to determine the influence of the autonomic nervous system...