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Keywords: non-alcoholic fatty liver disease
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Articles
Clin Sci (Lond) (2020) 134 (13): 1775–1799.
Published: 17 July 2020
...Lei Zhang; Zhi-Gang She; Hongliang Li; Xiao-Jing Zhang Non-alcoholic fatty liver disease (NAFLD) has become the fastest growing chronic liver disease, with a prevalence of up to 25% worldwide. Individuals with NAFLD have a high risk of disease progression to cirrhosis, hepatocellular carcinoma (HCC...
Articles
Clin Sci (Lond) (2017) 131 (4): 285–296.
Published: 20 January 2017
.... Induction of endogenous BAT function had a significant therapeutic impact on obesity, glucose tolerance and liver complications and is a potential new avenue for therapy of non-alcoholic fatty liver disease (NAFLD). Correspondence: Isabelle A. Leclercq (email isabelle.leclercq@uclouvain.be ). ©...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2015) 129 (12): 1097–1105.
Published: 13 October 2015
...Kate Hallsworth; Christian Thoma; Kieren G. Hollingsworth; Sophie Cassidy; Quentin M. Anstee; Christopher P. Day; Michael I. Trenell Although lifestyle changes encompassing weight loss and exercise remain the cornerstone of non-alcoholic fatty liver disease (NAFLD) management, the effect...
Articles
Clin Sci (Lond) (2015) 129 (9): 797–808.
Published: 07 August 2015
...-alcoholic steatohepatitis). chronic inflammation CX 3 CR1 dendritic cells liver fibrosis macrophages non-alcoholic fatty liver disease Previous studies have revealed the existence of at least two di-stinct monocyte subsets. Inflammatory monocytes are characte-rized as Ly6C high /CCR2...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2014) 127 (12): 655–663.
Published: 08 August 2014
...Daniel J. Cuthbertson; Andrew Irwin; Victoria S. Sprung; Helen Jones; Christopher J. A. Pugh; Christina Daousi; Valerie L. Adams; William E. Bimson; Fariba Shojaee-Moradie; Paul Richardson; A. Margot Umpleby; John P. Wilding; Graham J. Kemp Non-alcoholic fatty liver disease (NAFLD), characterized...
Articles
Clin Sci (Lond) (2014) 127 (7): 507–518.
Published: 25 June 2014
... Hospital (Garran, ACT, Australia). apoptosis endoplasmic reticulum stress inflammation insulin resistance non-alcoholic fatty liver disease • Previous studies have shown that counteracting ER stress using chemical chaperones such as TUDCA had a therapeutic benefit in obese and insulin...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2013) 124 (4): 279–287.
Published: 05 November 2012
... 7 2012 12 9 2012 12 9 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 liver fibrosis liver inflammation natural killer T-cell (NKT cell) non-alcoholic fatty liver disease • NF-κB activation is involved in the pathogenesis of NASH. Among...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2013) 124 (1): 53–63.
Published: 07 September 2012
...Adriana L. Burgueño; Tomas F. Gianotti; Noelia G. Mansilla; Carlos J. Pirola; Silvia Sookoian CVD (cardiovascular disease) is associated with abnormal liver enzymes, and NAFLD (non-alcoholic fatty liver disease) is independently associated with cardiovascular risk. To gain insights...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2012) 122 (11): 545–554.
Published: 10 February 2012
...Virginia Maina; Salvatore Sutti; Irene Locatelli; Matteo Vidali; Cristina Mombello; Cristina Bozzola; Emanuele Albano In humans, there is large inter-individual variability in the evolution of NAFLD (non-alcoholic fatty liver disease) to NASH (non-alcoholic steatohepatitis). To investigate...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2004) 106 (3): 261–268.
Published: 01 March 2004
... is implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In the present study, hepatic and plasma oxidative stress-related parameters were measured and correlated with clinical and histological findings in 31 NAFLD patients showing increased body mass index. Liver protein carbonyl content...
Articles
Clin Sci (Lond) (2004) 106 (3): 235–237.
Published: 01 March 2004
...Isabelle A. LECLERCQ This comment discusses the study by Videla and colleagues in this issue of Clinical Science in which they have analysed surgical liver biopsies from obese patients with non-alcoholic fatty liver disease and demonstrate that fatty liver is associated with a state of oxidative...