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1-8 of 8
Keywords: non-alcoholic steatohepatitis
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Articles
In Collection
New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (1): 65–85.
Published: 05 January 2023
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bile acids enterohepatic cycle gut microbiota non alcoholic fatty liver disease non-alcoholic steatohepatitis The array of bile acid species variably interact with receptors, resulting...
Articles
Sherouk Fouda, Anwar Khan, Stanley M.H. Chan, Ali Mahzari, Xiu Zhou, Cheng Xue Qin, Ross Vlahos, Ji-Ming Ye
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2103–2119.
Published: 06 September 2021
...Sherouk Fouda; Anwar Khan; Stanley M.H. Chan; Ali Mahzari; Xiu Zhou; Cheng Xue Qin; Ross Vlahos; Ji-Ming Ye Consumption of diet rich in fat and cigarette smoking (CS) are independent risk factors of non-alcoholic steatohepatitis (NASH), and they often occur together in some populations. The present...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (22): 2245–2264.
Published: 19 November 2019
... and concerted action of factors that contribute to the development of liver inflammation and eventually fibrosis. Here, we summarize fundamental molecular mechanisms underlying the pathogenesis of non-alcoholic steatohepatitis (NASH), how they are interrelated and possible translation to clinical applications...
Articles
Elisa Vivoli, Andrea Cappon, Stefano Milani, Benedetta Piombanti, Angela Provenzano, Erica Novo, Alessio Masi, Nadia Navari, Roberto Narducci, Guido Mannaioni, Gloriano Moneti, Claudia P. Oliveira, Maurizio Parola, Fabio Marra
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (20): 1793–1806.
Published: 09 September 2016
... (non-alcoholic steatohepatitis), is the most prevalent form of liver disease in Western countries [ 1 ]. More importantly, a diagnosis of NASH is associated with a higher risk of overall mortality and of liver-related mortality, indicating that strategies to prevent progression of liver injury...
Includes: Supplementary data
Articles
Gonenc Kocabay, Can Yucel Karabay, Yasar Colak, Vecih Oduncu, Arzu Kalayci, Taylan Akgun, Ahmet Guler, Cevat Kirma
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (4): 297–304.
Published: 22 October 2013
...Gonenc Kocabay; Can Yucel Karabay; Yasar Colak; Vecih Oduncu; Arzu Kalayci; Taylan Akgun; Ahmet Guler; Cevat Kirma The presence of the metabolic syndrome is a strong predictor for the presence of NASH (non-alcoholic steatohepatitis) in patients with NAFLD (non-alcoholic fatty liver disease...
Articles
Ying-Ying Yang, Yi-Tsau Huang, Tung-Hu Tsai, Ming-Chih Hou, Fa-Yauh Lee, Shou-Dong Lee, Han-Chieh Lin
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (12): 669–680.
Published: 10 August 2012
...-adrenergic agonist MTX (methoxamine). Besides promoting hepatic fibrosis, the role of hyperleptinaemia in the modulation of vascular response in NASH (non-alcoholic steatohepatitis) rat livers remains unknown. The aim of the present study was to explore the possible links between hyperleptinaemia...
Articles
Sara Galastri, Elena Zamara, Stefano Milani, Erica Novo, Angela Provenzano, Wanda Delogu, Francesco Vizzutti, Salvatore Sutti, Irene Locatelli, Nadia Navari, Elisa Vivoli, Alessandra Caligiuri, Massimo Pinzani, Emanuele Albano, Maurizio Parola, Fabio Marra
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (7): 459–471.
Published: 07 June 2012
...) (or monocyte chemoattractant protein-1) regulates inflammatory cell infiltration in the liver and adipose tissue, favouring steatosis. However, its role in the pathogenesis of steatohepatitis is still uncertain. In the present study, we investigated the development of non-alcoholic steatohepatitis induced...
Articles
Piero Portincasa, Ignazio Grattagliano, Bernhard H. Lauterburg, Vincenzo O. Palmieri, Giuseppe Palasciano, Frans Stellaard
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (2): 135–143.
Published: 13 July 2006
...) and in identifying altered metabolic pathways. The present study was conducted on 39 (20 lean and 19 obese) hypertransaminasemic patients with histologically proven NAFLD {ranging from simple steatosis to severe steatohepatitis [NASH (non-alcoholic steatohepatitis)] and fibrosis} and 28 (20 lean and eight overweight...