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Keywords: non-alcoholic steatohepatitis (NASH)Close
Marta B. Afonso, Pedro M. Rodrigues, Tânia Carvalho, Marta Caridade, Paula Borralho, Helena Cortez-Pinto, Rui E. Castro, Cecília M.P. Rodrigues
Clin Sci (Lond) (2015) 129 (8): 721–739.
Published: 22 July 2015
... and the metabolic syndrome. NAFLD encompasses a spectrum of liver dysfunction ranging from simple fatty liver or hepatic steatosis to hepatic necrosis and inflammation, characteristic of non-alcoholic steatohepatitis (NASH). Further, NAFLD may potentially progress to severe long-term consequences, including...
Hédia Boujedidi, Olivier Robert, Alexandre Bignon, Anne-Marie Cassard-Doulcier, Marie-Laure Renoud, Hélène Gary-Gouy, Patrice Hemon, Hugo Tharinger, Sophie Prévot, Françoise Bachelerie, Sylvie Naveau, Dominique Emilie, Karl Balabanian, Gabriel Perlemuter
Clin Sci (Lond) (2015) 128 (4): 257–267.
Published: 17 October 2014
... is key in the progression of non-alcoholic steatohepatitis (NASH). An abnormal response of CD4 + T-cells from obese mice to the chemotactic effect of CXCL12 has been reported but the mechanism involved in this process and relevance in patients are unknown. We aimed to explore the mechanism involved...
Includes: Supplementary data
Satish C. Kalhan, John Edmison, Susan Marczewski, Srinivasan Dasarathy, Lourdes L. Gruca, Carole Bennett, Clarita Duenas, Rocio Lopez
Clin Sci (Lond) (2011) 121 (4): 179–189.
Published: 04 May 2011
... 30 3 2011 30 3 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 insulin resistance methionine non-alcoholic steatohepatitis (NASH) phenylalanine steatohepatitis urea NAFLD (non-alcoholic fatty liver disease) constitutes a spectrum ranging from...
Clin Sci (Lond) (2010) 118 (6): 397–400.
Published: 14 December 2009
... a progressive liver condition with NASH developing and worsening over time to cirrhosis (for review see [ 1 ]). β-oxidation fatty liver lipogenesis non-alcoholic steatohepatitis (NASH) peroxisome-proliferator-activated receptor (PPAR) phosphatase and tensin homologue deleted on chromosome 10 (PTEN...
Clin Sci (Lond) (2010) 118 (6): 401–410.
Published: 14 December 2009
...-alcoholic steatohepatitis (NASH) peroxisome-proliferator-activated receptor (PPAR) phosphatase and tensin homologue deleted on chromosome 10 (PTEN) sterol-regulatory-element-binding protein-1c (SREBP-1c) Table 1 Characteristics and biochemical changes of AlbCrePten flox/flox mice exposed...
Clin Sci (Lond) (2009) 116 (7): 539–564.
Published: 02 March 2009
...) to discuss extra- and intra-hepatic mechanisms contributing to the pathogenesis of NAFLD, a better understanding of which may help in the development of novel treatments for this condition. diabetes inflammation mitochondrion non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis...
Clin Sci (Lond) (2008) 115 (5): 141–150.
Published: 01 August 2008
... 1 2008 7 2 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 insulin resistance liver non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) obesity Case reports describing the development of liver disease progressing...